Angiostrongyliasis detected by next-generation sequencing in a ELISA-negative eosinophilic meningitis: A case report

被引：8

作者：

Zou, Yueli ^{[1
]}

Guan, Hongzhi ^{[2
]}

Wu, Honglong ^{[3
]}

Bu, Hui ^{[1
]}

Yan, Litian ^{[1
]}

Zhu, Yifei ^{[1
]}

He, Junying ^{[1
]}

机构：

[1] Hebei Med Univ, Hosp 2, Dept Neurol, Shijiazhuang, Hebei, Peoples R China

[2] Peking Union Med Coll & Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Neurol, Beijing, Peoples R China

[3] BGI Shenzhen, BGI Tianjin, Tianjin Med Lab, Tianjin, Peoples R China

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2020年 / 97卷

关键词：

Eosinophilic meningitis; Cerebrospinal fluid; Next-generation sequencing; MENINGOENCEPHALITIS; DIAGNOSIS; CSF;

D O I：

10.1016/j.ijid.2020.05.108

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Next-generation sequencing (NGS) is an emerging method with the potential of pan-pathogen screening. This study described a case of eosinophilic meningitis (EoM) with enzyme-linked immunosorbent assay (ELISA)-negative results for Angiostrongylus cantonensis (A. cantonensis), Trichinella spiralis and Paragonimus westermani and a positive identification of A. cantonensis by NGS in the cerebrospinal fluid. (C) 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ncnd/4.0/).

引用

页码：177 / 179

页数：3

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