Validation of an HPLC analytical method for determination of pancuronium bromide in pharmaceutical injections

被引：9

作者：

Lopez Garcia, Pedro ^{[1
]}

Pereira Gomes, Fabio ^{[1
]}

Ines Rocha, Maria ^{[1
]}

Santoro, Miritello ^{[1
]}

Maria Kedor-Hackmann, Erika Rosa ^{[1
]}

机构：

[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Pharm, BR-05508900 Sao Paulo, Brazil

来源：

ANALYTICAL LETTERS | 2008年 / 41卷 / 10期

关键词：

high performance liquid chromatography; pancuronium bromide; validation of analytical method;

D O I：

10.1080/00032710802162095

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Pancuronium bromide is used with general anesthesia in surgery for muscle relaxation and as an aid to intubation. A high performance liquid chromatographic method was fully validated for the quantitative determination of pancuronium bromide in pharmaceutical injectable solutions. The analytical method was performed on an amino column (Luna 150mm4.6mm, 5m). The mobile phase was composed of acetonitrile:water containing 50mmol L-1 of 1-octane sulfonic acid sodium salt (20:80v/v) with a flow rate of 1.0mL min-1 and ultraviolet (UV) detection at 210nm. The proposed analytical method was compared with that described in the British Pharmacopoeia.

引用

页码：1895 / 1908

页数：14

共 50 条

[41] Analytical Method Development and Validation for HPLC-ECD Determination of Moxifloxacin in Marketed Formulations
Reddy, G. Phani Sekhar
Navyasree, K. S.
Jagadish, P. C.
Bhat, Krishnamurthy
PHARMACEUTICAL CHEMISTRY JOURNAL, 2018, 52 (07) : 674 - 679
[42] Analytical Method Development and Validation for HPLC-ECD Determination of Moxifloxacin in Marketed Formulations
G. Phani Sekhar Reddy
K. S. Navyasree
P. C. Jagadish
Krishnamurthy Bhat
Pharmaceutical Chemistry Journal, 2018, 52 : 674 - 679
[43] DEVELOPMENT AND VALIDATION OF A HPLC ANALYTICAL METHOD FOR DETERMINATION OF ELLAGIC ACID IN EPILOBIUM ANGUSTIFOLIUM EXTRACT
Kadam, P., V
Yadav, K. N.
Bhingare, C. L.
Patil, M. J.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2019, 10 (03): : 1300 - 1306
[44] DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR DETERMINATION OF AN ASSOCIATION OF AMPICILLINS IN LYOPHILIZED POWDER FOR INJECTION BY HPLC
Prata Cione, Ana Paola
Liberale, Marcio Jose
da Silva, Paulo Marcos
QUIMICA NOVA, 2010, 33 (01): : 203 - U230
[45] Validation of An HPLC Method for The Determination of Some Β-Lactams Antibiotics Using A Green Analytical Technique
Nguyen, Thoai Dang
Phuong, Anh Tran Thi
Truong, Quoc-Ky
INDONESIAN JOURNAL OF PHARMACY, 2024, 35 (03): : 540 - 548
[46] Development and Validation of RP-HPLC Method for the Determination of Adefovir Dipivoxil in Bulk and in Pharmaceutical Formulation
Ahmed, Zaheer
Gopinath, B.
Shetty, A. Sathish Kumar
Sridhar, B. K.
E-JOURNAL OF CHEMISTRY, 2009, 6 (02) : 469 - 474
[47] DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR THE DETERMINATION OF METRONIDAZOLE BENZOATE AND RELATED IMPURITES IN BULK AND PHARMACEUTICAL FORMULATIONS
Melikyan, Levon A.
Martirosyan, Simak S.
Grigoryan, Rosa S.
Topchyan, Hakob V.
Davtyan, Tigran K.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2013, 4 (07): : 2594 - 2599
[48] Validation of an HPLC method for the determination of fleroxacin and its photo-degradation products in pharmaceutical forms
Djurdjevic, P
Laban, A
Jelikic-Stankov, M
ANNALI DI CHIMICA, 2004, 94 (1-2) : 71 - 83
[49] Development and Validation of a Stability-Indicating HPLC Method for the Determination of Acarbose in Pharmaceutical Dosage Forms
Mohammadi, Ali (alimohammadi@tums.ac.ir), 1600, Pleiades journals (73):
[50] Validation of an HPLC Method for the Determination of Diclofenac Diethylamine and Three of Its Impurities in a Gel Pharmaceutical Form
El Kacemi, Mounir
El Orche, Aimen
Elhamdaoui, Omar
Laouni, Amine
Azougagh, Mohamed
Karrouchi, Khalid
Bouatia, Mustapha
El Karbane, Miloud
JOURNAL OF AOAC INTERNATIONAL, 2023, 106 (06) : 1443 - 1454

← 1 2 3 4 5 →