Treatment of Zollinger-Ellison Syndrome

被引：16

作者：

Tomassetti, Paola ^{[1
]}

Campana, Davide ^{[1
]}

Piscitelli, Lydia ^{[1
]}

Mazzotta, Elena ^{[1
]}

Brocchi, Emilio ^{[1
]}

Pezzilli, Raffaele ^{[1
]}

Corinaldesi, Roberto ^{[1
]}

机构：

[1] Univ Bologna, Policlin S Orsola Malpighi, Dept Internal Med & Gastroenterol, I-40138 Bologna, Italy

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2005年 / 11卷 / 35期

关键词：

Gastrinoma; Zollinger-Ellison Syndrome; MEN; 1; Proton pump inhibitors; Somatostatin analogs; Chemoembolization;

D O I：

10.3748/wjg.v11.i35.5423

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

In this article, we have reviewed the main therapeutic measures for the treatment of Zollinger-Ellison syndrome (ZES). Review of the literature was based on computer searches (Pub-Med, Index Medicus) and personal experiences. We have evaluated all the measures now available for treating patients with sporadic gastrinomas or gastrinomas associated with Multiple Endocrine Neoplasia Type 1, (MEN 1) including medical therapy such as antisecretory drugs and somatostatin analogs (SST), chemotherapy and chemoembolization, and surgical procedures. In ZES patients, the best therapeutic procedure is surgery which, if radical, can be curative. Medical treatment can be the best palliative therapy and should be used, when possible, in association with surgery, in a multimodal therapeutic approach. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.

引用

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页码：5423 / 5432

页数：10

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