Synthesis of Protein-Based, Rod-Shaped Particles from Spherical Templates using Layer-by-Layer Assembly

被引：39
|
作者：
Zhou, Zhimin [1 ,2 ,3 ]
Anselmo, Aaron C. [1 ]
Mitragotri, Samir [1 ]
机构：
[1] Univ Calif Santa Barbara, Dept Chem Engn, Santa Barbara, CA 93106 USA
[2] Chinese Acad Med Sci, Inst Biomed Engn, Tianjin 300192, Peoples R China
[3] Peking Union Med Coll, Key Lab Biomed Mat Tianjin, Tianjin 300192, Peoples R China
来源：
ADVANCED MATERIALS | 2013年 / 25卷 / 19期
基金：
美国国家科学基金会;
关键词：
bovine serum albumin (BSA); Layer-by-layer; non-spherical particles; nanomedicine; nanorod; NANOTUBES; NANOPARTICLES; GEOMETRY; RELEASE;
D O I：
10.1002/adma.201300220
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Nanorods provide distinct advantages over their spherical counterparts for targeted drug delivery. Here, a novel method is described for the synthesis of biocompatible protein nanorods from spherical polystyrene templates using the layer-by-layer (LBL) technique. These nanorods can be used as a vehicle for the delivery of therapeutic agents to diseased sites. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2723 / 2727
页数：5
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