Hypothalamic Inflammation: Marker or Mechanism of Obesity Pathogenesis?

被引：150
|
作者：
Thaler, Joshua P.
Guyenet, Stephan J.
Dorfman, Mauricio D.
Wisse, Brent E.
Schwartz, Michael W. [1 ]
机构：
[1] Univ Washington, Sch Med, Diabet & Obes Ctr Excellence, Seattle, WA 98195 USA
来源：
DIABETES | 2013年 / 62卷 / 08期
基金：
美国国家卫生研究院;
关键词：
NF-KAPPA-B; LEPTIN RESISTANCE; INSULIN-RESISTANCE; ENERGY-EXPENDITURE; FOOD-INTAKE; DIET; BEHAVIOR; MICE; ACCUMULATION; ACTIVATION;
D O I：
10.2337/db12-1605
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：2629 / 2634
页数：6
相关论文
共 50 条
  • [21] MECHANISM OF THE DEVELOPMENT OF OBESITY IN ANIMALS WITH HYPOTHALAMIC LESIONS
    BROBECK, JR
    PHYSIOLOGICAL REVIEWS, 1946, 26 (04) : 541 - 559
  • [22] Evidence Linking Loss of Hypothalamic Perineuronal Nets to Obesity Pathogenesis
    Alonge, Kimberly M.
    Dorfman, Mauricio D.
    Scarlett, Jarrad M.
    Melhorn, Susan J.
    Ye, Yuanchao
    Hu, Shannon J. W.
    Francis, Kendra L.
    Hendrickson, Aarun
    Cui, Katherine
    Morton, Gregory J.
    Schur, Ellen
    Thaler, Joshua
    Schwartz, Michael W.
    DIABETES, 2022, 71
  • [23] Hypothalamic Inflammation in Human Obesity Is Mediated by Environmental and Genetic Factors
    Kreutzer, Carina
    Peters, Soenke
    Schulte, Dominik M.
    Fangmann, Daniela
    Tuerk, Kathrin
    Wolff, Stephan
    van Eimeren, Thilo
    Ahrens, Markus
    Beckmann, Jan
    Schafmayer, Clemens
    Becker, Thomas
    Kerby, Tina
    Rohr, Axel
    Riedel, Christian
    Heinsen, Femke-Anouska
    Degenhardt, Frauke
    Franke, Andre
    Rosenstiel, Philip
    Zubek, Nana
    Henning, Christian
    Freitag-Wolf, Sandra
    Dempfle, Astrid
    Psilopanagioti, Aristea
    Petrou-Papadaki, Helen
    Lenk, Lennart
    Jansen, Olav
    Schreiber, Stefan
    Laudes, Matthias
    DIABETES, 2017, 66 (09) : 2407 - 2415
  • [24] Minireview: Inflammation and Obesity Pathogenesis: The Hypothalamus Heats Up
    Thaler, Joshua P.
    Schwartz, Michael W.
    ENDOCRINOLOGY, 2010, 151 (09) : 4109 - 4115
  • [25] Bacteria, viruses, and hypothalamic inflammation: Potential new players in obesity
    Wierucka-Rybak, Magdalena
    Bojanowska, Ewa
    POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ, 2014, 68 : 271 - 279
  • [26] The key role of inflammation in the pathogenesis and management of obesity and CVD
    Boutari, Chrysoula
    Hill, Michael A.
    Procaccini, Claudio
    Matarese, Giuseppe
    Mantzoros, Christos S.
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2023, 145
  • [27] Childhood Obesity, Hypothalamic Inflammation, and the Onset of Puberty: A Narrative Review
    Tzounakou, Anastasia-Maria
    Stathori, Galateia
    Paltoglou, George
    Valsamakis, Georgios
    Mastorakos, George
    Vlahos, Nikolaos F.
    Charmandari, Evangelia
    NUTRIENTS, 2024, 16 (11)
  • [28] Hypothalamic inflammation in high fat diet-induced obesity
    Kim, Min-Seon
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2016, 120 : S26 - S26
  • [29] The Role of Obesity in Covid-19 Pathogenesis and Inflammation
    Currey, Joshua M.
    Qin, Xuebin
    Blair, Robert
    Midkiff, Cecily
    Rappaport, Jay
    Kolls, Jay
    Mauvais-Jarvis, Franck
    Maness, Nicholas
    CIRCULATION, 2022, 146
  • [30] Mechanism of inflammation and neuroendocrine dysregulation in obesity
    Machado Calzerra, Natalia Tabosa
    Resende de Almeida Dias, Julia Rafaella
    Timani, Kevin
    Paixao Vieira, Renata Layne
    de Queiroz, Thyago Moreira
    ACTA BRASILIENSIS, 2020, 4 (01): : 70 - 76
12345