Single and Dual Pathologies of the Temporal Lobe: Effects on Cognitive Function in Children with Epilepsy

被引:16
|
作者
Bigel, Marla G. [2 ]
Smith, Mary Lou [1 ,2 ]
机构
[1] Univ Toronto, Dept Psychol, Mississauga, ON L5L 1C6, Canada
[2] Hosp Sick Children, Dept Psychol, Toronto, ON M5G 1X8, Canada
关键词
temporal lobe epilepsy; children; neuropathology; neuropsychology; hippocampal sclerosis; tumor; cortical dysplasia; cognition;
D O I
10.1006/ebeh.2000.0146
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The neuropathologies associated with temporal lobe epilepsy (TLE) are heterogeneous. The performance of 61 children with single pathology of hippocampal sclerosis (HS), temporal lobe tumor, or cortical dysplasia (CD) or dual pathology of HS + tumor or HS + CD was examined on measures of intelligence, language, memory, and executive function. Children with single pathologies performed significantly better than did children with HS + CD on all standardized measures of IQ. Children with tumors performed significantly better than children with dual pathology on receptive vocabulary. These results support prior research of an association between neuropathology and cognitive function in children with epilepsy and extend the findings to include additional neuropathologies and measures of cognitive functioning. (C) 2001 Academic Press
引用
收藏
页码:37 / 45
页数:9
相关论文
共 50 条
  • [31] Cognitive functioning in patients with temporal lobe epilepsy
    Altdungarova, R.
    Altayeva, B.
    Arinova, O.
    Zhalimbetova, G.
    Nyamdorzhiyn, G.
    EPILEPSIA, 2006, 47 : 162 - 162
  • [32] Cognitive analysis in temporal lobe epilepsy patients
    Oddo, S
    Consalvo, D
    Solis, P
    Giagante, B
    Silva, W
    Centurion, E
    D'Alessio, L
    Saidon, P
    Cochen, S
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2003, 214 (1-2) : 81 - 81
  • [33] Benzyl isothiocyanate ameliorates cognitive function in mice of chronic temporal lobe epilepsy
    Chang, Xiaoyu
    Zhou, Hongzhen
    Peng, Nan
    Gao, Tengwei
    Gong, Yanan
    Guo, Yan
    La, Haiyan
    Ma, Li
    Wu, Haiya
    Wen, Yujun
    Zhang, Rui
    FRONTIERS IN NEUROLOGY, 2024, 15
  • [34] Cognitive status in patients with temporal lobe epilepsy
    Tani, A.
    Adali, P. N.
    EPILEPSIA, 2023, 64 : 512 - 513
  • [35] The neurobiology of cognitive disorders in temporal lobe epilepsy
    Brian Bell
    Jack J. Lin
    Michael Seidenberg
    Bruce Hermann
    Nature Reviews Neurology, 2011, 7 : 154 - 164
  • [37] Cognitive and memory impairment in temporal lobe epilepsies with different pathologies
    Aykut-Bingol, C
    Torun, G
    Midi, I
    Agan, K
    Tuncer, N
    EPILEPSIA, 2005, 46 : 314 - 314
  • [38] The neurodevelopmental impact of childhood onset temporal lobe epilepsy on brain structure and function and the risk of progressive cognitive effects
    Hermann, BP
    Seidenberg, M
    Bell, B
    DO SEIZURES DAMAGE THE BRAIN, 2002, 135 : 429 - 438
  • [39] Protective Effects of Allantoin on Neural Cells of Hippocampal Region and Cognitive Function in a Mouse Model of Temporal Lobe Epilepsy
    Farsani, Mohsen Eslami
    Shahmir, Ahmad Hatami
    Seyedebrahimi, Reihaneh
    Ababzadeh, Shima
    Moslehi, Azam
    Tafaroji, Javad
    ARCHIVES OF EPILEPSY, 2024, 30 (01): : 1 - 6
  • [40] The cognitive effects of amygdalohippocampal deep brain stimulation in patients with temporal lobe epilepsy
    Miatton, Marijke
    Van Roost, Dirk
    Thiery, Evert
    Carrette, Evelien
    Vonck, Kristl
    Meurs, Alfred
    Vingerhoets, Guy
    Boon, Paul
    EPILEPSY & BEHAVIOR, 2011, 22 (04) : 759 - 764