NS5A: A new target for antiviral drugs in the treatment of hepatitis C virus infection

被引：6
|
作者：
Debes, Jose D. [1 ]
Smith, Coleman I. [1 ]
机构：
[1] Univ Minnesota, Plymouth, MN USA
来源：
HEPATOLOGY | 2012年 / 56卷 / 03期
关键词：
GENOTYPE; 1; PROTEIN; REPLICATION; INHIBITOR; BMS-790052;
D O I：
10.1002/hep.25696
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：797 / 799
页数：3
相关论文
共 50 条
  • [41] Role of hepatitis C virus proteins (C, NS3, NS5A) in hepatic oncogenesis
    Kasprzak, Aldona
    Adamek, Agnieszka
    HEPATOLOGY RESEARCH, 2008, 38 (01) : 1 - 26
  • [42] NS5A Sequence Heterogeneity and Mechanisms of Daclatasvir Resistance in Hepatitis C Virus Genotype 4 Infection
    Zhou, Nannan
    Hernandez, Dennis
    Ueland, Joseph
    Yang, Xiaoyan
    Yu, Fei
    Sims, Karen
    Yin, Philip D.
    McPhee, Fiona
    JOURNAL OF INFECTIOUS DISEASES, 2016, 213 (02): : 206 - 215
  • [43] A role for domain I of the hepatitis C virus NS5A protein in virus assembly
    Yin, Chunhong
    Goonawardane, Niluka
    Stewart, Hazel
    Harris, Mark
    PLOS PATHOGENS, 2018, 14 (01)
  • [44] Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus
    Bobardt, Michael D.
    Cheng, Guofeng
    de Witte, Lot
    Selvarajah, Suganya
    Chatterji, Udayan
    Sanders-Beer, Brigitte E.
    Geijtenbeek, Teunis B. H.
    Chisari, Francis V.
    Gallay, Philippe A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (14) : 5525 - 5530
  • [45] Fast Hepatitis C Virus RNA Elimination and NS5A Redistribution by NS5A Inhibitors Studied by a Multiplex Assay Approach
    Liu, Dandan
    Ji, Juan
    Ndongwe, Tanya P.
    Michailidis, Eleftherios
    Rice, Charles M.
    Ralston, Robert
    Sarafianos, Stefan G.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (06) : 3482 - 3492
  • [46] Mutations in NS5A region of hepatitis C virus genome correlate with presence of NS5A antibodies and response to interferon therapy for most common European hepatitis C virus genotypes
    Frangeul, L
    Cresta, P
    Perrin, M
    Lunel, F
    Opolon, P
    Agut, H
    Huraux, JM
    HEPATOLOGY, 1998, 28 (06) : 1674 - 1679
  • [47] Inhibitory peptides derived from Hepatitis C virus NS5A for reducing clinical symptoms of dengue virus infection
    Lee, Younghoon
    Seo, Minjun
    Yun, Suk-hyun
    Yu, Minyeong
    Kim, Hyo Jin
    Cho, Hye Won
    Byeon, Hee Won
    Park, Seong Ok
    Uyangaa, Erdenebileg
    Jeon, Hyunjin
    Lee, Minhyeong
    Kwon, Young Do
    Eo, Seong Kug
    ANTIVIRAL RESEARCH, 2024, 231
  • [48] In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS5A Inhibitor Pibrentasvir
    Ng, Teresa I.
    Krishnan, Preethi
    Pilot-Matias, Tami
    Kati, Warren
    Schnell, Gretja
    Beyer, Jill
    Reisch, Thomas
    Lu, Liangjun
    Dekhtyar, Tatyana
    Irvin, Michelle
    Tripathi, Rakesh
    Maring, Clarence
    Randolph, John T.
    Wagner, Rolf
    Collins, Christine
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2017, 61 (05)
  • [49] Hepatitis C treatment with Sofosbuvir and NS5A inhibitor in patients with an addiction
    Trabut, Jean-Baptiste
    Barrault, Camille
    Charlot, Helene
    Carmona, Damien
    Kini-Matondo, Willy
    Questel, Franck
    Hezode, Christophe
    HEPATOLOGY, 2015, 62 : 752A - 752A
  • [50] Approaches to hepatitis C treatment and cure using NS5A inhibitors
    Kohler, James J.
    Nettles, James H.
    Amblard, Franck
    Hurwitz, Selwyn J.
    Bassit, Leda
    Stanton, Richard A.
    Ehteshami, Maryam
    Schinazi, Raymond F.
    INFECTION AND DRUG RESISTANCE, 2014, 7 : 41 - 56
12345