Homeostasis of intestinal immune regulation

被引：26
|
作者：
Annacker, O [1 ]
Powrie, F [1 ]
机构：
[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England
来源：
MICROBES AND INFECTION | 2002年 / 4卷 / 05期
基金：
英国惠康基金;
关键词：
inflammatory bowel disease; immune regulation; T-cell homeostasis; interleukin-2; receptor; regulatory T cells;
D O I：
10.1016/S1286-4579(02)01574-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Regulatory CD4 T cells with the capacity to inhibit potentially harmful immune responses have been described in various experimental systems. Although the observations are converging towards the naturally activated CD25(+) CD4 T cells as a major population responsible for this protection, there is still considerable disagreement on the molecular and cellular requirements involved to achieve a stable immune homeostasis in vivo. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码：567 / 574
页数：8
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