Homeostasis of intestinal immune regulation

被引：26

作者：

Annacker, O ^{[1
]}

Powrie, F ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 05期

基金：

英国惠康基金;

关键词：

inflammatory bowel disease; immune regulation; T-cell homeostasis; interleukin-2; receptor; regulatory T cells;

D O I：

10.1016/S1286-4579(02)01574-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Regulatory CD4 T cells with the capacity to inhibit potentially harmful immune responses have been described in various experimental systems. Although the observations are converging towards the naturally activated CD25(+) CD4 T cells as a major population responsible for this protection, there is still considerable disagreement on the molecular and cellular requirements involved to achieve a stable immune homeostasis in vivo. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：567 / 574

页数：8

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