An Efficient Microwave Assisted Synthesis and Antimicrobial Activty of 1,2,3-Triazolyl-pyrrolidinyl-quinolinolines

被引：4
|
作者：
Pradeep, M. [1 ]
Vishnuvardhan, M. [1 ]
Krishna, V. Bala [1 ]
Raju, R. Madhusudhan [1 ]
机构：
[1] Osmania Univ, Dept Chem, Hyderabad 500007, Telangana, India
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2019年 / 89卷 / 02期
关键词：
VilsmeierHaack reaction; ClaisenSchmidt condensation; Click reaction; microwave irradiation; antibacterial activity; antifungal activity; BIOLOGICAL EVALUATION; DERIVATIVES; PYRROLIDINE; ULTRASOUND;
D O I：
10.1134/S1070363219020233
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel series of 1,2,3-triazolyl-pyrrolidinyl-quinolinolines are synthesised by the Click reaction of alkynes with aromatic azides catalysed by CuI under microwave assisted and conventional conditions. All synthesized 1,2,3-triazoles are screened for their in vitro antimicrobial activity against different bacterial and fungal pathogens. Majority of the synthesized compounds demonstrate moderate to good inhibition zones compared to the standard drugs.
引用
收藏
页码：313 / 318
页数：6
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