Investigation into the correlation between efficacy and KL:KH affinity ratio for the dopamine D2S receptor

被引:0
|
作者
Spragg, EJ [1 ]
Charlton, SJ [1 ]
Scaramellini, CM [1 ]
机构
[1] Novartis Horsham Res Ctr, Horsham RH12 5AB, W Sussex, England
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
340P
引用
收藏
页数:1
相关论文
共 50 条
  • [1] D2s dopamine receptor mediates phospholipase D and antiproliferation
    Senogles, SE
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2003, 209 (1-2) : 61 - 69
  • [2] Antagonist-Binding Conformation of the Dopamine D2S Receptor
    Payne, Philip W.
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 462A - 462A
  • [3] The D2s dopamine receptor stimulates phospholipase D activity: A novel signaling pathway for dopamine
    Senogles, SE
    MOLECULAR PHARMACOLOGY, 2000, 58 (02) : 455 - 462
  • [4] Differential Voltage-sensitivities Of Agonists At The Dopamine D2S Receptor
    Sahlholm, Kristoffer
    Marcellino, Daniel
    Nilsson, Johanna
    Fuxe, Kjell
    Arhem, Peter
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 369A - 369A
  • [5] Random mutagenesis of the third intracellular loop of the D2s dopamine receptor
    Quasney, MW
    Senogles, SE
    FASEB JOURNAL, 1998, 12 (08): : A1462 - A1462
  • [6] Autoreceptor Function of the Dopamine D2 Receptor Splice Variants D2S and D2L
    Neve, Kim Arthur
    Robinson, Brooks G.
    Condon, Alec F.
    Yorgason, Jordan T.
    McLain, Duncan E.
    Asad, Naeem
    Dore, Timothy M.
    Borrelli, Emiliana
    Williams, John T.
    FASEB JOURNAL, 2019, 33
  • [7] Purification and characterization of the recombinant human dopamine D2S receptor from Pichia pastoris
    de Jong, LAA
    Grünewald, S
    Franke, JP
    Uges, DRA
    Bischoff, R
    PROTEIN EXPRESSION AND PURIFICATION, 2004, 33 (02) : 176 - 184
  • [8] Voltage-sensitivity at the human dopamine D2S receptor is agonist-specific
    Sahlholm, Kristoffer
    Marcellino, Daniel
    Nilsson, Johanna
    Fuxe, Kjell
    Arhem, Peter
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 377 (04) : 1216 - 1221
  • [9] The dopamine D4/D2 receptor antagonist affinity ratio as a predictor of anti-aggression medication efficacy
    El-Mallakh, Rif S.
    McKenzie, Courtney
    MEDICAL HYPOTHESES, 2013, 80 (05) : 530 - 533
  • [10] Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain
    Gonzalez, S.
    Rangel-Barajas, C.
    Peper, M.
    Lorenzo, R.
    Moreno, E.
    Ciruela, F.
    Borycz, J.
    Ortiz, J.
    Lluis, C.
    Franco, R.
    McCormick, P. J.
    Volkow, N. D.
    Rubinstein, M.
    Floran, B.
    Ferre, S.
    MOLECULAR PSYCHIATRY, 2012, 17 (06) : 650 - 662