New bis-Pyridinium Diquaternary Salts with Antimicrobial Properties

被引：0

作者：

Furdui, Bianca ^{[1
]}

Constantin, Oana ^{[2
]}

Tabacaru, Aurel ^{[3
]}

Dinica, Rodica Mihaela ^{[1
]}

机构：

[1] Dunarea de Jos Univ Galati, Fac Sci & Environm, Galati 800201, Romania

[2] Dunarea de Jos Univ Galati, Fac Food & Sci Engeneering, Galati 800008, Romania

[3] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

来源：

REVISTA DE CHIMIE | 2012年 / 63卷 / 07期

关键词：

pyridinium quaternary salts; antimicrobial activity; TGA analysis; SERIES;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of a new series of asymmetric bis-pyridinium diquaternary salts using a N-alkylation reaction of 1,2-bis(4-pyridyl)ethane with reactive halides is reported. The structures of the salts were fully characterized by IR, NMR and mass spectroscopy and elemental analysis. Their antimicrobial activity against food spoilage microorganisms was comparatively investigated. Some of these compounds were found to inhibit the growth of microorganisms (bacteria and fungus) in function of structure and doses. The thermal stability of all species was also determined by thermogravimetric analysis.

引用

页码：667 / 671

页数：5

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