Selective carriers of norepinephrine and ammonium ions: Ionophoric properties and molecular modelling studies of diester crown compounds containing a 1,3-bis(1H-pyrazol-1-yl)propane unit

被引:10
|
作者
RodriguezFranco, MI [1 ]
Fierros, M [1 ]
Martinez, A [1 ]
Navarro, P [1 ]
Conde, S [1 ]
机构
[1] CSIC,INST QUIM MED,E-28006 MADRID,SPAIN
关键词
D O I
10.1016/S0968-0896(96)00250-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ionophoric properties of dipyrazolic crowns and podands containing a 1,3-bis(1H-pyrazol-1-yl)propane unit in their structure are described. They show selectivity of ammonium vs alkali cations and interesting norepinephrine transport rates. A molecular modelling study has been used to elucidate the superstructures of the crown and ammonium cation complexes. (C) 1997, Elsevier Science Ltd.
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页码:363 / 367
页数:5
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