Design of a Micro-Electrode Cell for Programmable Lab-on-CMOS Platform

This paper presents a programmable lab-on-CMOS (LoCMOS) with micro-electrode cell array. Array structure is suitable for programmable like CMOS VLSIs. In order to improve the utilization, each micro-electrode cell is composed of actuation and sensing circuit. In addition, a CMOS-compatible extended drain MOSFET (EDMOS) is adopted under a 3V supply. This LoCMOS platform is composed of 1,800 microelectrodes with exploiting EDMOS to enable droplet actuations. Through its field programmability, the chip can successfully perform all microfluidic operations, droplet moving/cutting/mixing on a 2-dimenional microelectrode cell array. Implemented in 0.35um standard CMOS process, the LoCMOS platform demonstrates microfluidic functions and droplet detection. Measured results show successfully for actuation and real-time droplet location sensing.