Ventricular fibrillation associated with complete right bundle branch block

被引:20
|
作者
Aizawa, Yoshiyasu [1 ]
Takatsuki, Seiji [1 ]
Kimura, Takehiro [1 ]
Nishiyama, Nobuhiro [1 ]
Fukumoto, Kotaro [1 ]
Tanimoto, Yoko [1 ]
Tanimoto, Kojiro [1 ]
Miyoshi, Shunichiro [1 ]
Suzuki, Makoto [2 ]
Yokoyama, Yasuhiro [3 ]
Chinushi, Masaomi [4 ]
Watanabe, Ichiro [5 ]
Ogawa, Satoshi [6 ]
Aizawa, Yoshifusa [7 ]
Antzelevitch, Charles [8 ]
Fukuda, Keiichi [1 ]
机构
[1] Keio Univ, Sch Med, Dept Cardiol, Tokyo 1608582, Japan
[2] Kameda Med Ctr, Dept Cardiol, Chiba, Japan
[3] Tokyo Med & Dent Univ, Heart Rhythm Ctr, Tokyo, Japan
[4] Niigata Univ, Grad Sch Med & Dent Sci, Niigata, Japan
[5] Nihon Univ, Sch Med, Itabashi Hosp, Tokyo, Japan
[6] Mita Hosp, Int Univ Hlth & Welfare, Tokyo, Japan
[7] Tachikawa Med Ctr, Div Res & Dev, Niigata, Japan
[8] Masonic Med Res Lab, Utica, NY USA
基金
美国国家卫生研究院;
关键词
Sudden death; Idiopathic ventricular fibrillation; Right bundle branch block; Electrocardiogram; Brugada syndrome; ST SEGMENT ELEVATION; BRUGADA-SYNDROME; J-WAVES; AUGMENTATION; TACHYCARDIA; POPULATION; MECHANISM; BEPRIDIL; ONSET; MODE;
D O I
10.1016/j.hrthm.2013.03.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND A substantial number of patients with idiopathic ventricular fibrillation (IVF) present with no specific electrocardiographic (ECG) findings. OBJECTIVE To evaluate complete right bundle branch block (RBBB) in patients with IVF. METHODS Patients with IVF showing complete RBBB were included in the present study. Structural and primary electrical diseases were excluded, and provocation tests were performed to exclude the presence of spastic angina or Brugada syndrome (BrS). The prevalence of complete RBBB and the clinical and ECG parameters were compared either in patients with IVF who did not show RBBB or in the general population and age and sex comparable controls with RBBB. RESULTS Of 96 patients with IVF, 9 patients were excluded for the presence of BrS. Of 87 patients studied, 10 (11.5%) patients showed complete RBBB. None had structural heart diseases, BrS, or coronary spasms. The mean age was 44 +/- 15 years, and 8 of 10 patients were men. Among the ECG parameters, only the QRS duration was different from that of the other patients with IVF who did not show complete RBBB. Ventricular fibrillation recurred in 3:2 in the form of storms, which were well suppressed by isoproterenol. Complete RBBB was found less often in control subjects (1.37%; P <.0001), and the QRS duration was more prolonged in patients with IVF: 139 +/- 10 ms vs 150 +/- 14 ms (P = .0061). CONCLUSIONS Complete RBBB exists more often in patients with IVF than in controls. A prolonged (IRS complex suggests a conduction abnormality. Our findings warrant further investigation of the role of RBBB in the development of arrhythmias in patients with IVF.
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页码:1028 / 1035
页数:8
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