Objective: Postoperative emesis after strabismus surgery continues to be a problem, despite the use of anti-emetic measures. The purpose of this study was to identify an anesthetic technique associated with the lowest incidence of vomiting after squint surgery. Materials and methods: A prospective, randomized, double-blind study was conducted to evaluate the effect of Acupuncture at P6 versus ultrasound guided medial canthus peribulbar block with propofol infusion on emesis in 180 pediatric patients undergoing strabismus correction. Results: The incidence of emesis was significantly lower in the peribulbar (4/90, 4.4%) compared to the acupuncture group (17/90, 18.8%) (p < 0.01). Conclusion: Among the two techniques, peribulbar block with propofol-based anesthesia is the technique with the lowest incidence of postoperative emesis compared to the acupuncture technique. [Ashraf Darwish, Mona Raafat, Rehab Sami, Mohamed Hisham, and Hala Bahy Acupuncture versus Ultrasound-Guided Peribulbar Block in Pediatric Strabismus Correction: A Prospective Randomized Study] Life Science Journal 2012; 9(1):888-891]. (ISSN: 1097-8135). http://www.lifesciencesite.com. 130