Antimicrobial Stewardship in Pediatrics How Every Pediatrician Can Be a Steward

被引:52
|
作者
Hyun, David Y. [1 ,2 ]
Hersh, Adam L. [3 ]
Namtu, Katie [4 ,5 ]
Palazzi, Debra L. [6 ,7 ]
Maples, Holly D. [8 ]
Newland, Jason G. [9 ]
Saiman, Lisa [10 ]
机构
[1] Childrens Natl Med Ctr, Div Pediat Infect Dis, Washington, DC 20010 USA
[2] George Washington Univ, Sch Med, Dept Pediat, Washington, DC 20052 USA
[3] Univ Utah, Dept Pediat, Div Infect Dis, Salt Lake City, UT USA
[4] Univ S Florida, All Childrens Hosp, Dept Pharm, St Petersburg, FL 33701 USA
[5] Johns Hopkins Med, St Petersburg, FL USA
[6] Baylor Coll Med, Dept Pediat, Infect Dis Sect, Houston, TX 77030 USA
[7] Texas Childrens Hosp, Houston, TX 77030 USA
[8] Univ Arkansas Med Sci, Div Pharm Practice, Coll Pharm, Little Rock, AR 72205 USA
[9] Univ Missouri Kansas City, Div Pediat Infect Dis, Childrens Mercy Hosp & Clin, Kansas City, MO USA
[10] Columbia Univ, Dept Pediat, New York, NY 10027 USA
关键词
INFECTIOUS-DISEASES SOCIETY; OF-THE-ART; CLOSTRIDIUM-DIFFICILE; ANTIBIOTIC EXPOSURE; IMPACT; CARE; THERAPY; PROGRAM; INITIATION; CHILDREN;
D O I
10.1001/jamapediatrics.2013.2241
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Antimicrobial stewardship (AS) programs are effective in improving clinical outcomes associated with antimicrobial therapies while improving patient safety by reducing adverse events and development of bacterial resistance. Understanding the basic principles of AS is essential to the successful development and implementation of AS strategies. Identifying and developing strategies to address barriers and challenges to AS can facilitate the establishment of financial, administrative, and organizational support, and agreement and participation by individual prescribers. Review of published outcomes of AS demonstrates the effectiveness in reducing unnecessary antimicrobial use and adverse events such as Clostridium difficile infections. We also illustrate the need for further research and expansion of AS activities to office-based practices and communities by using novel and innovative AS strategies and by influencing regional and national policies.
引用
收藏
页码:859 / 866
页数:8
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