Reversal of Opioid-Induced Gastric Dysfunction in a Critically III Burn Patient After Methylnaltrexone

被引：21
|
作者：
Woo, Michael [1 ]
O'Connor, Michael [1 ]
Yuan, Chun-Su [1 ]
Moss, Jonathan [1 ]
机构：
[1] Univ Chicago, Dept Anesthesia & Crit Care, Chicago, IL 60637 USA
来源：
ANESTHESIA AND ANALGESIA | 2008年 / 107卷 / 06期
关键词：
D O I：
10.1213/ane.0b013e31818556d3
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Peripheral-acting mu opiate receptor antagonists have been extensively studied for the treatment of opiate-induced constipation in advanced illness for the prophylaxis of postoperative ileus. We document the first intensive care patient to receive methylnaltrexone in an attempt to facilitate enteral nutrition. Gastric residuals markedly decreased and enteral feeding increased after administration of IV methylnaltrexone. The patient's ileus resolved coincident with the first injection.
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页码：1965 / 1967
页数：3
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