Recent advances in combinatorial chemistry applied to development of anti-HIV drugs

被引：11
|
作者：
Pettersson, S
Clotet-Codina, I
Esté, JA
Borrell, JI
Teixidó, J
机构：
[1] Univ Ramon Llull, IQS, GEM, E-08017 Barcelona, Spain
[2] Univ Autonoma Barcelona, Hosp Univ Germans Trias & Pujol, Lab Retrovirol IrsiCaixa, Badalona 08916, Spain
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2006年 / 6卷 / 01期
关键词：
combinatorial chemistry; synthesis; anti-HIV drugs; high throughput screening;
D O I：
10.2174/138955706775197820
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with high throughput screening assays has allowed the discovery and optimization of novel lead anti-HIV compounds.
引用
收藏
页码：91 / 108
页数：18
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