A Role of Genomic Copy Number Variation in the Complex Behavioral Phenotype of Alcohol Dependence: A Commentary

被引：0
|
作者：
Urban, Alexander E. [1 ]
机构：
[1] Stanford Univ, Sch Med, Dept Genet, Dept Psychiat & Behav Sci, Palo Alto, CA 94304 USA
来源：
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH | 2012年 / 36卷 / 09期
关键词：
Complex Disorder; Genome Variation; Segmental Duplications; Regulatory Regions; Genome Technology; DUPLICATIONS; VARIANTS;
D O I：
10.1111/j.1530-0277.2012.01915.x
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
In their paper Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence Lin and colleagues report on the association between alcohol dependence and 2 duplication CNVs in the genome sequence, one containing 8 genes within its boundaries and another that contains no genes. In this commentary, I point out some of the opportunities and challenges that arise from such a finding.
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页码：1483 / 1486
页数：4
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