Fresh Frozen Plasma Administration in the Neonatal Intensive Care Unit Evidence-Based Guidelines

被引：16

作者：

Motta, Mario ^{[1
]}

Del Vecchio, Antonio ^{[2
]}

Chirico, Gaetano ^{[1
]}

机构：

[1] Spedali Civili Brescia, Childrens Hosp Brescia, Neonatol & Neonatal Intens Care Unit, I-25123 Brescia, Italy

[2] ASL Bari, Di Venere Hosp, Neonatal Intens Care Unit, Div Neonatol,Dept Womens & Childrens Hlth, I-70012 Brescia, Italy

来源：

CLINICS IN PERINATOLOGY | 2015年 / 42卷 / 03期

关键词：

Fresh frozen plasma; Transfusion; Guidelines; Coagulation tests; Neonate; PARTIAL EXCHANGE-TRANSFUSION; RANDOMIZED CONTROLLED-TRIAL; HUMAN COAGULATION SYSTEM; INTRAVENTRICULAR HEMORRHAGE; CLINICAL-USE; DEVELOPMENTAL HEMOSTASIS; THERAPEUTIC HYPOTHERMIA; MULTIORGAN DYSFUNCTION; TEMPERATURE; NEWBORNS;

D O I：

10.1016/j.clp.2015.04.013

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Neonates receiving fresh frozen plasma (FFP) should do so according to evidence-based guidelines so as to reduce inappropriate use of this life-saving and costly blood product and to minimize associated adverse effects. The consensus-based uses of FFP in neonatology involve neonates with active bleeding and associated coagulopathy. However, because of limited and poor-quality evidence, considerable FFP utilization occurs outside these recommendations. In this review, we describe what we conclude are currently the best practices for the use of FFP in neonates, including interpreting neonatal coagulation tests and strategies for reducing unnecessary FFP transfusions.

引用

页码：639 / 650

页数：12

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