To PFKFB3 or Not to PFKFB3, That Is the Question

被引:2
|
作者
Branco, Cristina [1 ]
Johnson, Randall S. [1 ,2 ]
机构
[1] Univ Cambridge, Dept Physiol Dev & Neurosci, Cambridge CB2 3EG, England
[2] Karolinska Inst, Dept Cell & Mol Biol, S-17177 Stockholm, Sweden
关键词
ANGIOGENESIS; GLYCOLYSIS;
D O I
10.1016/j.ccell.2016.11.007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In this issue of Cancer Cell, Cantelmo et al. describe how reduction of PFKFB3 enzyme activity can promote vascular normalization. The authors show in turn how this affects vascular permeability and can ultimately improve the efficacy of chemotherapeutic agents.
引用
收藏
页码:831 / 831
页数:1
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