A combined in vitro, in vivo and in silico approach to develop and optimise a novel antiepileptic strategy in neonatal seizures

被引：0
|
作者：
Donovan, M. [1 ]
O'Brien, F. E. [2 ]
Boylan, G. B. [3 ]
Griffin, B. T. [1 ]
Cryan, J. F. [4 ]
机构：
[1] Natl Univ Ireland Univ Coll Cork, Sch Pharm, Cork, Ireland
[2] Natl Univ Ireland Univ Coll Cork, Alimentary Pharmabiot Ctr, Cork, Ireland
[3] Natl Univ Ireland Univ Coll Cork, Dept Paediat & Child Hlth, Cork, Ireland
[4] Natl Univ Ireland Univ Coll Cork, Dept Anat & Neurosci, Cork, Ireland
来源：
EUROPEAN NEUROPSYCHOPHARMACOLOGY | 2014年 / 24卷
关键词：
BRAIN;
D O I：
10.1016/S0924-977X(14)70011-2
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
P.1.009
引用
收藏
页码：S10 / S10
页数：1
相关论文
共 50 条
  • [21] Novel approach to the analysis of in vitro in vivo relationships
    Polli, JE
    Crison, JR
    Amidon, GL
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1996, 85 (07) : 753 - 760
  • [22] Design, synthesis, in vivo and in silico evaluation of novel benzothiazole-hydrazone derivatives as new antiepileptic agents
    Himanshu Singh
    Rajnish Kumar
    Avijit Mazumder
    Ranjeet Kumar Salahuddin
    Bharti Yadav
    Vimal Chauhan
    Km Datt
    Mohd. Mustaqeem Shabana
    Medicinal Chemistry Research, 2022, 31 : 1431 - 1447
  • [23] Design, synthesis, in vivo and in silico evaluation of novel benzothiazole-hydrazone derivatives as new antiepileptic agents
    Singh, Himanshu
    Kumar, Rajnish
    Mazumder, Avijit
    Salahuddin
    Yadav, Ranjeet Kumar
    Chauhan, Bharti
    Datt, Vimal
    Shabana, Km
    Abdullah, Mohd. Mustaqeem
    MEDICINAL CHEMISTRY RESEARCH, 2022, 31 (09) : 1431 - 1447
  • [24] An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis
    Hung, Sze Wan
    Liang, Bo
    Gao, Yating
    Zhang, Ruizhe
    Tan, Zhouyurong
    Zhang, Tao
    Chung, Pui Wah Jacqueline
    Chan, Tak Hang
    Wang, Chi Chiu
    FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [25] TARGETING CALCIUM-PERMEABLE AMPA RECEPTORS, A NOVEL STRATEGY FOR CONTROLLING NEONATAL SEIZURES
    Talos, D. M.
    Rakhade, S.
    Zhou, C.
    Jensen, F. E.
    JOURNAL OF NEUROCHEMISTRY, 2009, 108 : 45 - 45
  • [26] In Vitro, In Silico, and In Vivo Analyses of Novel Aromatic Amidines against Trypanosoma cruzi
    Santos, Camila C.
    Lionel, Jessica R.
    Peres, Raiza B.
    Batista, Marcos M.
    da Silva, Patricia B.
    de Oliveira, Gabriel M.
    da Silva, Cristiane F.
    Batista, Denise G. J.
    Souza, Sandra Maria O.
    Andrade, Carolina H.
    Neves, Bruno J.
    Braga, Rodolpho C.
    Patrick, Donald A.
    Bakunova, Svetlana M.
    Tidwell, Richard R.
    Soeiro, Maria de Nazare C.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2018, 62 (02)
  • [27] In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist
    Puls, Kristina
    Olive-Marti, Aina-Leonor
    Pach, Szymon
    Pinter, Birgit
    Erli, Filippo
    Wolber, Gerhard
    Spetea, Mariana
    PHARMACEUTICALS, 2022, 15 (06)
  • [28] In Silico, In Vitro, and Ex Vivo Biological Activity of Some Novel Mebeverine Precursors
    Milusheva, Miglena
    Gledacheva, Vera
    Stefanova, Iliyana
    Pencheva, Mina
    Mihaylova, Rositsa
    Tumbarski, Yulian
    Nedialkov, Paraskev
    Cherneva, Emiliya
    Todorova, Mina
    Nikolova, Stoyanka
    BIOMEDICINES, 2023, 11 (02)
  • [29] In silico, in vitro and in vivo approach in understanding the functional relationship between ergosterol and Rubisco
    Mitra, J.
    Narad, P.
    Paul, P. K.
    PHOTOSYNTHETICA, 2016, 54 (04) : 517 - 523
  • [30] New In Vitro-In Silico Approach for the Prediction of In Vivo Performance of Drug Combinations
    Correia, Cristiana
    Ferreira, Abigail
    Santos, Joana
    Lapa, Rui
    Yliperttula, Marjo
    Urtti, Arto
    Vale, Nuno
    MOLECULES, 2021, 26 (14):
12345