Copper-mediated synthesis of α-trifluoromethylthio- and seleno-α,β-unsaturated carbonyl compounds

被引：67
|
作者：
Zhu, Peitao [1 ]
He, Xing [1 ]
Chen, Xiaoqing [1 ]
You, Yi [1 ]
Yuan, Yaofeng [1 ]
Weng, Zhiqiang [1 ]
机构：
[1] Fuzhou Univ, Dept Chem, Fuzhou 350108, Fujian, Peoples R China
来源：
TETRAHEDRON | 2014年 / 70卷 / 03期
基金：
高等学校博士学科点专项科研基金; 中国国家自然科学基金;
关键词：
Trifluoromethylthiolation; Trifluoromethylselenolation; alpha-Halo-alpha; beta-unsaturated carbonyl compounds; Copper reagent; ARYL BORONIC ACIDS; CATALYZED TRIFLUOROMETHYLATION; NUCLEOPHILIC TRIFLUOROMETHYLTHIOLATION; OXIDATIVE TRIFLUOROMETHYLTHIOLATION; FLUORINATED ETHERS; TERMINAL ALKYNES; CHEMISTRY; THIOETHERS; RESONANCE; BROMIDES;
D O I：
10.1016/j.tet.2013.11.093
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel route to the synthesis of alpha-trifluoromethylthio- and seleno-alpha,beta-unsaturated carbonyl compounds via a copper-mediated trifluoromethylthiolation/trifluoromethylselenolation of alpha-halo-alpha,beta-unsaturated carbonyl substrates is reported. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：672 / 677
页数：6
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