Hair cortisol concentrations predict change in girls' depressive symptoms

被引：5

作者：

Sandstrom, Andrea ^{[1
]}

Daoust, Andrew R. ^{[1
]}

Russell, Evan ^{[2
]}

Koren, Gideon ^{[2
]}

Hayden, Elizabeth P. ^{[1
]}

机构：

[1] Univ Western Ontario, Dept Psychol, London, ON, Canada

[2] Univ Western Ontario, Dept Physiol Pharmacol, London, ON, Canada

来源：

EUROPEAN JOURNAL OF DEVELOPMENTAL PSYCHOLOGY | 2021年 / 18卷 / 02期

基金：

加拿大健康研究院;

关键词：

Hair cortisol; depression; development; SALIVARY CORTISOL; PSYCHIATRIC-DISORDERS; MAJOR DEPRESSION; STRESS; CHILDREN; ASSOCIATIONS; BIOMARKER; RESPONSES; HUMANS; MEMORY;

D O I：

10.1080/17405629.2020.1774359

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Hypothalamic-Pituitary-Adrenal (HPA) axis activity is related to negative mental health outcomes, including depression. Most developmental research uses salivary cortisol to index HPA activity; however, hair cortisol concentrations (HCCs) reflect cortisol production over extended periods of time. While HCCs have been linked to adult depression, their relationship to the development of children's depressive symptoms is unclear. We assessed HCCs in 60 seven-year-old community-dwelling girls who were followed up one year later. In broader models, girls' age 7 HCCs were positively associated with age 8 depressive symptoms at a trend level, indicating that HCCs may be related to mental health early in development.

引用

页码：184 / 198

页数：15

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