Correlation between cerebrospinal fluid routine and microscopic examination with clinicopathological parameters in patients with meningitis

Background: Cerebrospinal fluid examination is very useful and important in patients with neurological disease such as meningitis. CSF examination with quantification of polymorphs, lymphocytes and total count are the standard procedure in suspected case of infection. Our objective is to determine the correlation between clinicopathological parameters, routine and microscopic values. Material and Method: Total of 145 patient's reports included who were clinically suspected and underwent lumbar puncture from January 1st to 31st December 2021. Result: Meningitis was diagnosed in 82 male and 63 female patients over one year period. Fever was present in 99.3% patients with 65.5% experiencing headache, 56% vomiting with 68.9% experiencing neck stiffness and 73.1% had rash on the body. All symptoms showed significant p-value except headache when correlated with age group. Clinicopathological parameters significantly correlated with routine and microscopic values. Conclusion: CSF parameters are very useful as point of care tool for assessing patients with meningitis. Our study showed a very significant correlation between laboratories with clinicopathological parameters which can help clinicians for proper management of disease.