SECTOR LASER PHOTOCOAGULATION FOR THE PREVENTION OF MACULAR EDEMA AFTER PLAQUE RADIOTHERAPY FOR UVEAL MELANOMA A Pilot Study

被引：27
|
作者：
Materin, Miguel A. [1 ,2 ]
Bianciotto, Carlos G. [2 ]
Wu, Chengqing [3 ]
Shields, Carol L. [2 ]
机构：
[1] Yale Univ, Sch Med, Dept Ophthalmol, Ocular Oncol Sect, New Haven, CT 06443 USA
[2] Thomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USA
[3] Yale Univ, Sch Med, Dept Publ Hlth, New Haven, CT 06443 USA
来源：
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2012年 / 32卷 / 08期
关键词：
eye; uvea; melanoma; plaque radiotherapy; macular edema; sector laser; sector panretinal photocoagulation; INTRAVITREAL TRIAMCINOLONE ACETONIDE; RADIATION MACULOPATHY; CHOROIDAL MELANOMA; DIABETIC-RETINOPATHY; CONSECUTIVE PATIENTS; TUMOR-CONTROL; COMPLICATIONS; BRACHYTHERAPY; PAPILLOPATHY; IRRADIATION;
D O I：
10.1097/IAE.0b013e3182437e70
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Objective: To investigate the role of sector laser photocoagulation for prevention of macular edema after plaque radiotherapy for uveal melanoma. Methods: Noncomparative, pilot interventional case series. The main outcome measure was optical coherence tomography-evident macular edema. Results: A total of 29 patients had sector laser photocoagulation (sector panretinal photocoagulation) and sub-Tenon triamcinolone injection. The median tumor thickness and base was 3.3 mm and 10.0 mm. The median radiation dose and rate to the macula was 2,944 cGy and 31.0 cGy/hour. At the 12-month and 24-months follow-up, cystoid macular edema was found in 17% and 24% of the sector panretinal photocoagulation group. There were no major side effects registered. Conclusion: Sector panretinal photocoagulation in combination with sub-Tenon triamcinolone appears to show potential as a safe and beneficial intervention for the prevention of macular edema after plaque radiotherapy for uveal melanoma in this series. RETINA 32:1601-1607, 2012
引用
收藏
页码：1601 / 1607
页数：7
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