Oncolytic Virotherapy

被引：57
|
作者：
Sze, Daniel Y. [1 ]
Reid, Tony R. [3 ]
Rose, Steven C. [2 ]
机构：
[1] Stanford Univ, Sch Med, Div Intervent Radiol, Stanford Canc Ctr, Stanford, CA 94305 USA
[2] Univ Calif San Diego, Div Intervent Radiol, San Diego, CA 92103 USA
[3] Univ Calif San Diego, Moores Canc Ctr, Div Med Oncol, La Jolla, CA 92093 USA
来源：
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY | 2013年 / 24卷 / 08期
关键词：
PHASE-I TRIAL; CLINICAL-TRIAL; REPLICATION-COMPETENT; ADENOVIRUS ONYX-015; VIRUS NV1020; I/II TRIAL; CANCER; INJECTION; THERAPY; JX-594;
D O I：
10.1016/j.jvir.2013.05.040
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Oncolytic Virotherapy is an emerging technology that uses engineered viruses to treat malignancies. Viruses can be designed with biological specificity to infect Cancerous cells preferentially, and to replicate in these cells exclusively. Malignant cells may be killed directly by overwhelming viral infection and lysis, which releases additional viral particles, to infect neighboring cells and distant metastases. Viral infections may also activate the immune system,, unmask stealthy tumor antigens, and aid the immune system to recognize and attack neoplasms. Delivery of live virus particles is potentially complex, and may require the expertise of the interventional community.
引用
收藏
页码：1115 / 1122
页数：8
相关论文
共 50 条
  • [1] Oncolytic virotherapy
    Russell, Stephen J.
    Peng, Kah-Whye
    Bell, John C.
    NATURE BIOTECHNOLOGY, 2012, 30 (07) : 658 - 670
  • [2] Oncolytic virotherapy
    Cervantes-Garcia, Daniel
    Ortiz-Lopez, Rocio
    Mayek-Prez, Netzahualcoyotl
    Rojas-Martinez, Augusto
    ANNALS OF HEPATOLOGY, 2008, 7 (01) : 34 - 45
  • [3] Oncolytic virotherapy
    Stephen J Russell
    Kah-Whye Peng
    John C Bell
    Nature Biotechnology, 2012, 30 : 658 - 670
  • [4] Oncolytic virotherapy
    Al-Shammari, Ahmed Majeed
    Piccaluga, Pier Paolo
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 10
  • [5] Personalizing Oncolytic Virotherapy
    Hamdan, Firas
    Fusciello, Manlio
    Cerullo, Vincenzo
    HUMAN GENE THERAPY, 2023, 34 (17-18) : 870 - 877
  • [6] Oncolytic Virotherapy for Neuroblastoma
    Ramirez, Manuel
    Garcia-Castro, Javier
    Alemany, Ramon
    DISCOVERY MEDICINE, 2010, 10 (54) : 387 - 393
  • [7] Advances in oncolytic virotherapy
    Russell, Stephen J.
    Bell, John C.
    Engeland, Christine E.
    McFadden, Grant
    COMMUNICATIONS MEDICINE, 2022, 2 (01):
  • [8] Oncolytic virotherapy as immunotherapy
    Melcher, Alan
    Harrington, Kevin
    Vile, Richard
    SCIENCE, 2021, 374 (6573) : 1325 - 1326
  • [9] What is oncolytic virotherapy?
    Cockle, Julia V.
    Scott, Karen J.
    ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 2018, 103 (01): : 43 - 45
  • [10] Cytokines in oncolytic virotherapy
    Pol, Jonathan G.
    Workenhe, Samuel T.
    Konda, Prathyusha
    Gujar, Shashi
    Kroemer, Guido
    CYTOKINE & GROWTH FACTOR REVIEWS, 2020, 56 : 4 - 27
12345