In-situ and controllable synthesis of graphene-gold nanoparticles/molecularly imprinted polymers composite modified electrode for sensitive and selective rutin detection

被引:17
|
作者
Guo, Qianjuan [1 ]
Hu, Feilong [2 ]
Yang, Xin [1 ,3 ,4 ]
Yang, Jinhua [1 ]
Yang, Shufeng [2 ]
Chen, Xiongwen [1 ]
Wu, Feng [1 ]
Minteer, Shelley D. [4 ]
机构
[1] Huaihua Univ, Huaihua Key Lab Preparat Ceram Mat & Devices, Hunan Engn Lab Preparat Technol Polyvinyl Alcohol, Huaihua 418000, Peoples R China
[2] Guangxi Univ Nationalities, Guangxi Key Lab Chem & Engn Forest Prod, Nanning 530006, Peoples R China
[3] Huaihua Univ, Key Lab Res & Utilizat Ethnomed Plant Resources H, Huaihua 418000, Peoples R China
[4] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA
关键词
Rutin; Graphene-gold nanoparticles; Molecularly imprinted polymers; Screen-printed electrodes; In-situ; Controllable; CERIUM OXIDE NANOCOMPOSITES; ELECTROCHEMICAL SENSORS; VOLTAMMETRIC DETECTION; PASTE ELECTRODE;
D O I
10.1016/j.microc.2020.105254
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Identification and quantification of rutin is critical to pharmaceutical quality control and pharmacokinetic study. Herein, we report on a disposable electrochemical sensor based on in-situ and controllable synthesis of graphene (Gr)-gold nanoparticles (AuNPs) and molecularly imprinted polymers (MIPs) composite modified screen-printed electrodes (SPEs) for sensitive and selective rutin detection. Both Gr-AuNPs and MIPs were step by step formed on SPEs via electrochemical reduction and polymerization processes. The compositions, morphologies, and electrochemical properties of composite were investigated. After optimization of experimental conditions, the linear detection range recorded by the current responses of SPEs vertical bar Gr-AuNPs/MIPs electrode to rutin was 0.04 to 60.0 mu M (R = 0.9988). A limit of detection of 0.014 mu M (S/N = 3) was achieved. Due to the enhanced electrochemical performance resulting from synergistic effects of Gr-AuNPs and MIPs, the electrochemical sensor showed good anti-interference ability, long-term stability, and acceptable reproducibility. More, it was successfully employed to analyze rutin in medicinal tablets with good accuracy and recovery.
引用
收藏
页数:8
相关论文
共 50 条
  • [21] Highly selective and sensitive biosensor for cysteine detection based on in situ synthesis of gold nanoparticles/graphene nanocomposites
    Zhang, Yang
    Yang, Ankang
    Zhang, Xiaofang
    Zhao, Hong
    Li, Xiangjun
    Yuan, Zhuobin
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2013, 436 : 815 - 822
  • [22] Synthesis of Water-Dispersible Molecularly Imprinted Electroactive Nanoparticles for the Sensitive and Selective Paracetamol Detection
    Luo, Jing
    Ma, Qiang
    Wei, Wei
    Zhu, Ye
    Liu, Ren
    Liu, Xiaoya
    ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (32) : 21028 - 21038
  • [23] Highly selective and sensitive determination of dopamine by the novel molecularly imprinted poly(nicotinamide)/CuO nanoparticles modified electrode
    Li, Bingbing
    Zhou, Yusun
    Wu, Wei
    Liu, Min
    Mei, Surong
    Zhou, Yikai
    Jing, Tao
    BIOSENSORS & BIOELECTRONICS, 2015, 67 : 121 - 128
  • [24] A Label-Free Molecularly Imprinted Electrochemical Sensor Based on MXene Nanosheets Modified by Gold Nanoparticles for Sensitive and Selective Detection of Homocysteine
    Liu, Miao
    Pan, Bingchen
    Tang, Shanshan
    Wang, Wei
    Hou, Huipeng
    Xie, Bingteng
    Liang, Axin
    Luo, Aiqin
    JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 2022, 169 (08)
  • [25] Synthesis and characterization of a highly sensitive and selective electrochemical sensor based on molecularly imprinted polymer with gold nanoparticles modified screen-printed electrode for glycerol determination in wastewater
    Motia, Soukaina
    Bouchikhi, Benachir
    Llobet, Eduard
    El Bari, Nezha
    TALANTA, 2020, 216
  • [26] Synthesis and characterization of modified silica nanoparticles based molecularly imprinted polymers as a sensor for selective detection of pendimethalin from drinking water
    Noor, Muneera
    Iqbal, Kanwal Muhammad
    Kanwal, Tasmina
    Rehman, Khadija
    Ali, Mohsin
    Shah, Muhammad Raza
    JOURNAL OF MOLECULAR STRUCTURE, 2023, 1287
  • [27] A glassy carbon electrode modified with graphene nanoplatelets, gold nanoparticles and chitosan, and coated with a molecularly imprinted polymer for highly sensitive determination of prostate specific antigen
    Ya Ma
    Xiao-Lei Shen
    Qiang Zeng
    Li-Shi Wang
    Microchimica Acta, 2017, 184 : 4469 - 4476
  • [28] An Electrochemical Sensing Platform Based on Graphene Oxide and Molecularly Imprinted Polymer Modified Electrode for Selective Detection of Amoxicillin
    Guney, Sevgi
    Arslan, Taner
    Yanik, Serhat
    Guney, Orhan
    ELECTROANALYSIS, 2021, 33 (01) : 46 - 56
  • [29] A glassy carbon electrode modified with graphene nanoplatelets, gold nanoparticles and chitosan, and coated with a molecularly imprinted polymer for highly sensitive determination of prostate specific antigen
    Ma, Ya
    Shen, Xiao-Lei
    Zeng, Qiang
    Wang, Li-Shi
    MICROCHIMICA ACTA, 2017, 184 (11) : 4469 - 4476
  • [30] Determination of 17β-Estradiol based on electropolymerized-molecularly imprinted polymer on gold nanoparticles-graphene modified electrode
    Li, Tianhua
    Wang, De
    Lan, Hangzhen
    Gan, Ning
    CHEMICAL, MATERIAL AND METALLURGICAL ENGINEERING III, PTS 1-3, 2014, 881-883 : 93 - 97