Synthesis and antimicrobial activity of new 6-amino-4-phenyl-1-(N-alkoxyphthalimido)-3-methyl-1,4-dihydro pyrano[2,3-c]pyrazole-5-carbonitriles

被引：0

作者：

Jat, Jawahar L. ^{[1
]}

Bhambi, Dinesh ^{[1
]}

Chaudhary, Jyoti ^{[1
]}

Talesara, G. L. ^{[1
]}

机构：

[1] ML Sukhadia Univ, Dept Chem, Synthet Organ Chem Res Lab, Udaipur 313001, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 16卷 / 02期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Some alkoxyphthalimide derivatives of 6-amino-5-cyano-4-aryl-1,4-dihydropyrano [2,3-c] pyrazoles (6) were synthesized by the reaction of aromatic aldehydes, malononitrile and 3-methyl-1-(N-alkoxyphthalimido-2-pyrazolin-5-ones) using triethylbenzylammonium chloride [TEBA] as catalyst in aq media. The reaction has the advantage of good yield, less pollution; ease of separation and of being environmental friendly. Synthesized compounds were characterized by elemental analysis, IR, H-1 NMR and mass spectral studies. These compounds show moderate to good antibacterial and antifungal activity.

引用

页码：113 / 116

页数：4

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