All elasticity microscope .2. Experimental results

Initial experimental results ham a 50 MHz elasticity microscope are shown. Using methods discussed previously, we present measured displacement and normal axial strain fields ham a tissue mimicking phantom. Results from this homogenous gel are compared to a finite element simulation of the deformation experiment. The spatial resolution is estimated to be approximately 52 mu m for axial displacements, and 71 mu m fur normal axial strains. These estimates were further tested by imaging a phantom containing a hard cylindrical inclusion with cross-sectional diameter of 265 mu m. By examining the strain transition between regions in this image, the spatial resolution of the normal axial strain was verified to be at most 88 mu m. A typical experiment produces peak normal axial strain around 3%. These experiments demonstrate the potential of high frequency ultrasound as a means for elasticity microscopy. Preliminary deformation experiments are presented an porcine epidermis.