Lipoprotein(a): A unique risk factor for cardiovascular disease

被引：74
|
作者：
Anuurad, Erdembileg
Boffa, Michael B.
Koschinsky, Marlys L.
Berglund, Lars
机构：
[1] Univ Calif Davis, Dept Med, VA No Calif Hlth Care Syst, Med Ctr, Sacramento, CA 95817 USA
[2] Queens Univ, Dept Biochem, Kingston, ON K7L 3N6, Canada
来源：
CLINICS IN LABORATORY MEDICINE | 2006年 / 26卷 / 04期
关键词：
D O I：
10.1016/j.cll.2006.07.002
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Lipoprotein(a) (Lp(a)) is present in humans and primates. It has many properties in common with low-density lipoprotein, but Qcontains a unique protein moiety designated apo(a), which is linked to apolipoprotein B-100 by a single disulfide bond. International standards for Lp(a) measurement and optimized Lp(a) assays insensitive to isoform size are not yet widely available. Lp(a) is a risk factor for coronary artery disease, and smaller size apo(a) is associated with coronary artery disease. The physiologic role of Lp(a) is unknown.
引用
收藏
页码：751 / +
页数：24
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