Dendronized iron oxide nanoparticles as contrast agents for MRI

被引:108
|
作者
Basly, Brice [1 ]
Felder-Flesch, Delphine [1 ]
Perriat, Pascal [2 ]
Billotey, Claire [3 ]
Taleb, Jacqueline [3 ]
Pourroy, Genevieve [1 ]
Begin-Colin, Sylvie [1 ]
机构
[1] UMR CNRS UdS ECPM 7504, IPCMS, F-67034 Strasbourg, France
[2] CNRS INSA Lyon, UMR 5510, Etud Met Phys & Phys Mat Grp, F-69621 Villeurbanne, France
[3] Univ Lyon 1, Lab CREATIS LRMN, CNRS UMR 5220, INSA Lyon,INSERM,U630, F-69621 Villeurbanne, France
关键词
MAGNETITE-BASED NANOPARTICLES; DRUG-DELIVERY; BIOMEDICAL APPLICATIONS; COUPLING AGENT; RESONANCE; THERAPY; FUNCTIONALIZATION; STABILIZATION; DIAGNOSIS; OXIDATION;
D O I
10.1039/b920348f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Covalent attachment, through a phosphonate anchor, of hydrophilic pegylated dendrons on iron oxide nanoparticles results in versatile, robust, and highly relaxing MRI contrast agents.
引用
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页码:985 / 987
页数:3
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