GTP Cyclohydrolase I Phosphorylation and Interaction with GTP Cyclohydrolase Feedback Regulatory Protein Determine Endothelial Cell Tetrahydrobiopterin Levels and Nitric Oxide Production

被引：0
|
作者：
Li, Li [1 ]
Chen, Wei [1 ]
Salerno, John [2 ]
Harrison, David G. [1 ]
机构：
[1] Emory Univ, Atlanta, GA 30322 USA
[2] Kennesaw State Univ, Kennesaw, GA USA
来源：
HYPERTENSION | 2009年 / 54卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
引用
收藏
页码：E94 / E94
页数：1
相关论文
共 50 条
  • [21] Tetrahydrobiopterin and GTP cyclohydrolase I in a rat model of endotoxic shock: Relation to nitric oxide synthesis
    Hattori, Y
    Nakanishi, N
    Kasai, K
    Murakami, Y
    Shimoda, S
    EXPERIMENTAL PHYSIOLOGY, 1996, 81 (04) : 665 - 671
  • [22] GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation
    Cai, S
    Alp, NJ
    McDonald, D
    Smith, I
    Kay, J
    Canevari, L
    Heales, S
    Channon, KM
    CARDIOVASCULAR RESEARCH, 2002, 55 (04) : 838 - 849
  • [23] GTP cyclohydrolase I mRNA induction and tetrahydrobiopterin synthesis in human endothelial cells
    Hattori, Y
    Nakanishi, N
    Kasai, K
    Shimoda, SI
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1997, 1358 (01): : 61 - 66
  • [24] GTP cyclohydrolase I mRNA induction and tetrahydrobiopterin synthesis in human endothelial cells
    Hattori, Y.
    Nakanishi, N.
    Kasai, K.
    Shimoda, S.-I.
    B B A - Biomembranes, 1358 (01):
  • [25] Investigating the interaction between GTP-cyclohydrolase1 and its feedback regulatory protein
    Hussein, Dania
    Starr, Anna
    Heikal, Lannia
    Nandi, Manasi
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2012, 27 : S29 - S30
  • [26] Localization and function of GTP cyclohydrolase I feedback regulatory protein (GFRP) in rat brain
    Hirayama, K
    Shimoji, M
    Kojima, M
    Milstien, S
    Kapatos, G
    CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, 1997, : 619 - 622
  • [27] GTP cyclohydrolase I inhibition by the prototypic inhibitor 2,4-diamino-6-hydroxypyrimidine - Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein
    Xie, LJ
    Smith, JA
    Gross, SS
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (33) : 21091 - 21098
  • [28] GTP cyclohydrolase I is coinduced in hepatocytes stimulated to produce nitric oxide
    Geller, DA
    Di Silvio, M
    Billiar, TR
    Hatakeyama, K
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 276 (02) : 633 - 641
  • [29] Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
    Alp, NJ
    Mussa, S
    Khoo, J
    Cai, SJ
    Guzik, T
    Rockett, K
    Channon, KM
    CIRCULATION, 2003, 108 (17) : 27 - 27
  • [30] Regulation of GTP cyclohydrolase I activity by nitric oxide in human umbilical vein endothelial cells
    Shiraishi, H
    Kato, T
    Kuroda, R
    Sumi-Ichinose, C
    Ichinose, H
    Hagino, Y
    Nomura, T
    JAPANESE JOURNAL OF PHARMACOLOGY, 2002, 88 : 76P - 76P
12345