How and Why Are Irritability and Depression Linked?

被引：33

作者：

Vidal-Ribas, Pablo ^{[1
]}

Stringaris, Argyris ^{[2
]}

机构：

[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Social & Behav Sci Branch, NIH, 6710 Rockledge Dr,Bldg 6710B,Room 3153A, Bethesda, MD 20892 USA

[2] NIMH, Sect Clin & Computat Psychiat, NIH, 9000 Rockville Pike,Bldg 15k,Room 208, Bethesda, MD 20892 USA

来源：

CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA | 2021年 / 30卷 / 02期

关键词：

Irritability; Depression; Risk; Genetics; Prospective;

D O I：

10.1016/j.chc.2020.10.009

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Irritability, defined as an increased proneness to anger relative to peers at the same developmental level,1 is linked to depression. This review first distinguishes between two types of irritability, namely episodic irritability and chronic irritability. Then, the two types of associations between irritability and depression, namely cross-sectional and longitudinal, are described. Next, possible explanations are provided, mechanistic pathways that might explain the link between irritability and depression proposed,

引用

页码：401 / 414

页数：14

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