Respiratory syncytial virus infection

被引:430
|
作者
Simoes, EAF
机构
[1] Univ Colorado, Sch Med, Dept Pediat, Infect Dis Sect, Denver, CO 80218 USA
[2] Childrens Hosp, Denver, CO 80218 USA
来源
LANCET | 1999年 / 354卷 / 9181期
关键词
D O I
10.1016/S0140-6736(99)80040-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Respiratory syncytial virus (RSV), long recognised as the major viral pathogen of the lower respiratory tract of infants, has also been implicated in severe lung disease in adults, especially the elderly. This fact, and the demonstration that passive prophylaxis with either polyclonal or monoclonal antibody to RSV prevents severe lung disease in high-risk infants and children, has led to renewed interest in the immune mechanisms surrounding protection, and the development of vaccines.
引用
收藏
页码:847 / 852
页数:6
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