JAK/STAT signalling:: STAT cannot play with KEN and Barbie

被引:6
|
作者
Hombría, JCG [1 ]
Sotillos, S [1 ]
机构
[1] Univ Pablo de Olavide, CSIC, Ctr Andaluz Biol Desarrollo, Seville 41013, Spain
关键词
D O I
10.1016/j.cub.2006.01.021
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Transcriptional responses to the activation of a signalling pathway are cell-specific. New data show that the sequence-specific transcriptional repressors of the KEN/BCL-6 family play an important role in the selection of STAT targets in vertebrates and invertebrates, indicating that all STAT proteins may share this-ancestral mechanism.
引用
收藏
页码:R98 / R100
页数:3
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