The Optimization of Extraction of Cordycepin from Fruiting Body of Cordyceps militaris (L.) Link

被引：4

作者：

Zhang, Hong ^{[2
]}

Wang, Jun-Wei ^{[3
]}

Dong, Sheng-Zhong ^{[3
]}

Xu, Fang-Xu ^{[1
]}

Wang, Sheng-Hou ^{[1
]}

机构：

[1] Shenyang Normal Univ, Res Inst Special Fungus, Shenyang 110034, Liaoning, Peoples R China

[2] Hebei United Univ, Coll Life Sci, Tangshan 063000, Hebei, Peoples R China

[3] Shenyang Normal Univ, Fac Engn, Shenyang 110034, Liaoning, Peoples R China

来源：

BIOTECHNOLOGY, CHEMICAL AND MATERIALS ENGINEERING, PTS 1-3 | 2012年 / 393-395卷

关键词：

Cordyceps militaris; cordycepin; optimization extraction; high-performance liquid chromatography (HPLC);

D O I：

10.4028/www.scientific.net/AMR.393-395.1024

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The optimization of extraction of cordycepin from fruiting body of Cordyceps militaris YCC-01 by water extraction, ethanol extraction, ultrasonic extraction, and synergistic extraction is studied in this paper. The optimal conditions, water extraction at 85 degrees C for 2.5h plus ultrasonic extraction at 600W for 35min, were determined through high performance liquid chromatography (HPLC). The dried fruiting body of cordycepin content was 9.559 mg/g by this synergistic extraction method. The yield was 66.2% higher than the control group 85 degrees C water extraction 2.5h and 11.3% higher than the room temperature ultrasonic extraction 35min. This method has a short extraction time, low cost, low loss of active ingredients and other characteristics with good prospects.

引用

页码：1024 / +

页数：2

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