Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase

被引：11
|
作者：
Marson, CM
Rioja, AS
Brooke, G
Coombes, RC
Vigushin, DM
机构：
[1] UCL, Christopher Ingold Labs, Dept Chem, London WC1H 0AJ, England
[2] Univ London Imperial Coll Sci Technol & Med, Dept Canc Med, London W12 0NN, England
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2002年 / 12卷 / 02期
关键词：
D O I：
10.1016/S0960-894X(01)00718-1
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Cyclic acid anhydrides possessing a lipid chain have been shown to be a new class of non-peptidic inhibitors of geranylgeranyl protein-transferase type I (GGPTase-I). (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：255 / 259
页数：5
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