An Oncogenic Metabolic Switch Mediates Resistance to NOTCH1 Inhibition in T-ALL

被引：1
|
作者：
Herranz, Daniel [1 ]
Tosello, Valeria [1 ]
Ambesi-Impiombato, Alberto [1 ]
Castillo, Mireia [2 ]
Cordon-Cardo, Carlos [2 ]
Ferrando, Adolfo A. [3 ]
机构：
[1] Columbia Univ, Inst Canc Genet, New York, NY USA
[2] Mt Sinai Sch Med, Dept Pathol, New York, NY USA
[3] Columbia Univ, Inst Canc Genet, New York, NY USA
来源：
BLOOD | 2012年 / 120卷 / 21期
关键词：
D O I：
10.1182/blood.V120.21.285.285
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
285
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Chemical Genomic Screen Identifies Ionophores as Modulators of Notch1 in T-ALL
    Roti, Giovanni
    Ross, Kenneth N.
    Mecucci, Cristina
    Ferrando, Adolfo A.
    Aster, Jon C.
    Stegmaier, Kimberly
    BLOOD, 2008, 112 (11) : 81 - 81
  • [32] Overexpression of Notch1 Inducing T-ALL Phenotype and Promoting Angiogenesis in Zebrafish
    Shen, Lijing
    Chen, Fangyuan
    Qing, Kai
    Li, Xiang
    Liu, Haiyan
    BLOOD, 2016, 128 (22)
  • [33] Oncogenic signaling pathways and resistance to therapy in T-ALL
    Ferrando, Adolfo
    CANCER RESEARCH, 2016, 76
  • [34] Elevated Trib2 with Notch1 activation in pediatric/adult T-ALL
    Hannon, M.
    Lohan, F.
    Erbilgin, Y.
    O'Hagan, K.
    Mills, K.
    Ozbek, U.
    Keeshan, K.
    BRITISH JOURNAL OF HAEMATOLOGY, 2012, 157 : 6 - 6
  • [35] Prognostic significance of NOTCH1 and FBXW7 mutations in pediatric T-ALL
    Erbilgin, Yucel
    Sayitoglu, Muge
    Hatirnaz, Ozden
    Dogru, Omer
    Akcay, Arzu
    Tuysuz, Gulen
    Celkan, Tiraje
    Aydogan, Gonul
    Salcioglu, Zafer
    Timur, Cetin
    Yuksel-Soycan, Lebriz
    Ure, Umit
    Anak, Sema
    Agaoglu, Leyla
    Devecioglu, Omer
    Yildiz, Inci
    Ozbek, Ugur
    DISEASE MARKERS, 2010, 28 (06) : 353 - 360
  • [36] Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL
    Hannon, Maura M.
    Lohan, Fiona
    Erbilgin, Yucel
    Sayitoglu, Muge
    O'Hagan, Kathleen
    Mills, Ken
    Ozbek, Ugur
    Keeshan, Karen
    BRITISH JOURNAL OF HAEMATOLOGY, 2012, 158 (05) : 626 - 634
  • [37] Notch1 signaling is involved in regulating Foxp3 expression in T-ALL
    Xiaodan Luo
    Huo Tan
    Yueqiao Zhou
    Tiantian Xiao
    Chunyan Wang
    Yangqiu Li
    Cancer Cell International, 13
  • [38] Notch1 signaling is involved in regulating Foxp3 expression in T-ALL
    Luo, Xiaodan
    Tan, Huo
    Zhou, Yueqiao
    Xiao, Tiantian
    Wang, Chunyan
    Li, Yangqiu
    CANCER CELL INTERNATIONAL, 2013, 13
  • [39] NOTCH1 signaling is essential for leukemia initiating cell self-renewal in T-ALL
    Ma, Wenxue
    Gutierrez, Alejandro
    Wei, Ping
    Sadarangani, Anil
    Goff, Daniel J.
    Shih, Alice Y.
    Court, Angela C.
    Jiang, Qingfei
    Leu, Heather
    Wall, Russell H.
    Crews, Leslie A.
    Look, A. Thomas
    Jamieson, Catriona H. M.
    CANCER RESEARCH, 2012, 72
  • [40] Notch, a T-ALL order
    Osborne, Barbara A.
    BLOOD, 2011, 117 (10) : 2749 - 2750
12345