piRNA Rules of Engagement

被引：11
|
作者：
Svendsen, Joshua M. [1 ,2 ]
Montgomery, Taiowa A. [1 ]
机构：
[1] Colorado State Univ, Dept Biol, Ft Collins, CO 80523 USA
[2] Colorado State Univ, Cell & Mol Biol Program, Ft Collins, CO 80523 USA
来源：
DEVELOPMENTAL CELL | 2018年 / 44卷 / 06期
关键词：
C; ELEGANS; GERMLINE; RNA;
D O I：
10.1016/j.devcel.2018.03.006
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
piRNAs are known to silence transposable elements, but not all piRNAs match transposon sequences. Recent studies from Shen et al. (2018) and Zhang et al. (2018) identify rules for piRNA target recognition in Caenorhabditis elegans. Permissive pairing rules allow targeting of essentially all germline mRNAs, while protective mechanisms prevent silencing self-genes.
引用
收藏
页码：657 / 658
页数：2
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