Membrane protein architects: the role of the BAM complex in outer membrane protein assembly

被引：277

作者：

Knowles, Timothy J. ^{[2
]}

Scott-Tucker, Anthony ^{[1
]}

Overduin, Michael ^{[2
]}

Henderson, Ian R. ^{[1
]}

机构：

[1] Univ Birmingham, Div Immun & Infect, Birmingham B15 2TT, W Midlands, England

[2] Univ Birmingham, Canc Res UK Inst Canc Studies, Sch Canc Sci, Birmingham B15 2TT, W Midlands, England

来源：

NATURE REVIEWS MICROBIOLOGY | 2009年 / 7卷 / 03期

基金：

英国生物技术与生命科学研究理事会; 英国医学研究理事会;

关键词：

BETA-BARREL PROTEINS; ESCHERICHIA-COLI; CRYSTAL-STRUCTURE; BACTERIAL PROTEIN; CYTOPLASMIC MEMBRANE; FUNCTIONAL DOMAINS; CHAPERONE ACTIVITY; SECRETIN PULD; LIPID EXPORT; YAET COMPLEX;

D O I：

10.1038/nrmicro2069

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The folding of transmembrane proteins into the outer membrane presents formidable challenges to Gram-negative bacteria. These proteins must migrate from the cytoplasm, through the inner membrane and into the periplasm, before being recognized by the beta-barrel assembly machinery, which mediates efficient insertion of folded beta-barrels into the outer membrane. Recent discoveries of component structures and accessory interactions of this complex are yielding insights into how cells fold membrane proteins. Here, we discuss how these structures illuminate the mechanisms responsible for the biogenesis of outer membrane proteins.

引用

页码：206 / 214

页数：9

共 50 条

[21] Machinery for protein sorting and assembly in the mitochondrial outer membrane
Wiedemann, N
Kozjak, V
Chacinska, A
Schönfisch, B
Rospert, S
Ryan, MT
Pfanner, N
Meisinger, C
NATURE, 2003, 424 (6948) : 565 - 571
[22] Peptidoglycan maturation controls outer membrane protein assembly
Gideon Mamou
Federico Corona
Ruth Cohen-Khait
Nicholas G. Housden
Vivian Yeung
Dawei Sun
Pooja Sridhar
Manuel Pazos
Timothy J. Knowles
Colin Kleanthous
Waldemar Vollmer
Nature, 2022, 606 : 953 - 959
[23] The protein import and assembly machinery of the mitochondrial outer membrane
Taylor, RD
Pfanner, N
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2004, 1658 (1-2): : 37 - 43
[24] Structural Aspects of Bacterial Outer Membrane Protein Assembly
Calmettes, Charles
Judd, Andrew
Moraes, Trevor F.
PROKARYOTIC SYSTEMS BIOLOGY, 2015, 883 : 255 - 270
[25] Role of lipids in membrane protein assembly
Dowhan, W
Bogdanov, MV
FASEB JOURNAL, 2001, 15 (05): : A725 - A725
[26] Outer membrane protein folding mechanism: How does an OMP reach the active site of the BAM complex?
Williams, Patrick L.
Campbell, Conner
Scheyer, Matthew
Hussain, Mustakim
Begum, Afsana
Fonseca, Sebastian
Dabney, Peyton
Carter, Haley
Sanders, Charles R.
Lorigan, Gary A.
Sahu, Indra D.
BIOPHYSICAL JOURNAL, 2023, 122 (03) : 54A - 54A
[27] The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane
Gunasinghe, Sachith D.
Shiota, Takuya
Stubenrauch, Christopher J.
Schulze, Keith E.
Webb, Chaille T.
Fulcher, Alex J.
Dunstan, Rhys A.
Hay, Iain D.
Naderer, Thomas
Whelan, Donna R.
Bell, Toby D. M.
Elgass, Kirstin D.
Strugnell, Richard A.
Lithgow, Trevor
CELL REPORTS, 2018, 23 (09): : 2782 - 2794
[28] MEMBRANE ASSEMBLY OF THE OUTER-MEMBRANE PROTEIN OMPA OF ESCHERICHIA-COLI
KLOSE, M
STORIKO, A
STIERHOF, YD
HINDENNACH, I
MUTSCHLER, B
HENNING, U
JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (34) : 25664 - 25670
[29] The β-barrel assembly machinery (BAM) is required for the assembly of a primitive S-layer protein in the ancient outer membrane of Thermus thermophilus
Federico Acosta
Eloy Ferreras
José Berenguer
Extremophiles, 2012, 16 : 853 - 861
[30] The β-barrel assembly machinery (BAM) is required for the assembly of a primitive S-layer protein in the ancient outer membrane of Thermus thermophilus
Acosta, Federico
Ferreras, Eloy
Berenguer, Jose
EXTREMOPHILES, 2012, 16 (06) : 853 - 861

← 1 2 3 4 5 →