IL-22 from T Cells: Better Late than Never

被引:13
|
作者
Honda, Kenya [1 ,2 ,3 ]
机构
[1] Univ Tokyo, Grad Sch Med, Dept Immunol, Tokyo 1130033, Japan
[2] Res Ctr Allergy & Immunol, Yokohama, Kanagawa 2300045, Japan
[3] JST, CREST, Kawaguchi, Saitama 3320012, Japan
关键词
HOST-DEFENSE; DISEASE;
D O I
10.1016/j.immuni.2012.11.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Interleukin-22 (IL-22) enhances mucosal barrier function and is important in antimicrobial host defense. In this issue of Immunity, Basu et al. (2012) reveal that Th22 cells are the critical adaptive source of IL-22 during late-phase infection by Citrobacter rodentium.
引用
收藏
页码:952 / 954
页数:3
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