APOE and APOC1 genetic polymorphisms in age-associated memory impairment

被引：0

作者：

Bartrés-Faz, D

Clemente, IC

Junqué, C

Valveny, N

López-Alomar, A

Sánchez-Aldeguer, J

López-Guillén, A

Moral, P

机构：

[1] Univ Barcelona, Dept Psychiat & Clin Psychobiol, Barcelona 08036, Spain

[2] Univ Barcelona, Anthropol Unit, Dept Biol Anim, Barcelona, Spain

[3] Autonomous Univ Barcelona, EU Gimbernat, Barcelona, Spain

[4] Catalonian Inst Hlth, CAP, Barcelona, Spain

来源：

NEUROGENETICS | 2001年 / 3卷 / 04期

关键词：

apolipoproteins; genetic; memory; impairment; aging;

D O I：

暂无

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We studied the distribution of two genetic polymorphisms (APOE and APOC1) in a sample of 100 subjects fulfilling the NIMH criteria for age-associated memory impairment (AAMI) and 124 controls. We found significant associations both for APOE and APOC1 loci and their combinations with the AAMI condition. The findings in our sample suggest that memory-impaired subjects as described by the NIMH may be genetically differentiated from normally aging subjects in relation to these two polymorphisms and indicate the interest of considering variations in the APOC1 gene for further studies in cognitive aging.

引用

页码：215 / 219

页数：5

共 50 条

[41] Nootropic treatment and combined therapy in age-associated memory impairment
Israel, L
Myslinski, M
Kozarevic, D
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 1998, : 269 - 274
[42] Evidence that age-associated memory impairment is not a normal variant of aging
Goldman, WP
Morris, JC
ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 2001, 15 (02): : 72 - 79
[43] Age-associated memory impairment - Assessing the role of nitric oxide
Meyer, RC
Spangler, EL
Kametani, H
Ingram, DK
TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN: PRACTICAL APPROACHES TO INTERVENTION, 1998, 854 : 307 - 317
[44] Age-associated memory impairment - Normal aging or warning of dementia?
Hanninen, T
Soininen, H
DRUGS & AGING, 1997, 11 (06) : 480 - 489
[45] Genetic Variants and Haplotypes of TOMM40, APOE, and APOC1 are Related to the Age of Onset of Late-onset Alzheimer Disease in a Colombian Population
Ortega-Rojas, Jenny
Arboleda-Bustos, Carlos E.
Guerrero, Esneyder
Neira, Juan
Arboleda, Humberto
ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 2022, 36 (01): : 29 - 35
[46] TOMM40, APOE, and APOC1 in Primary Progressive Aphasia and Frontotemporal Dementia
Seripa, Davide
Bizzarro, Alessandra
Pilotto, Andrea
Palmieri, Orazio
Panza, Francesco
D'Onofrio, Grazia
Gravina, Carolina
Archetti, Silvana
Daniele, Antonio
Borroni, Barbara
Padovani, Alessandro
Masullo, Carlo
JOURNAL OF ALZHEIMERS DISEASE, 2012, 31 (04) : 731 - 740
[47] PHACTR1 and APOC1 genetic variants are associated with multi-vessel coronary artery disease
Al Hageh, Cynthia
O'Sullivan, Siobhan
Henschel, Andreas
Abchee, Antoine
Hantouche, Mireille
Iakovidou, Nantia
Issa, Taly
Chacar, Stephanie
Nader, Moni
Zalloua, Pierre A.
LIPIDS IN HEALTH AND DISEASE, 2024, 23 (01)
[48] Commentary on age-associated memory impairment, age-related cognitive decline and mild cognitive impairment
Ferris, SH
Kluger, A
AGING NEUROPSYCHOLOGY AND COGNITION, 1996, 3 (02) : 148 - 153
[49] AGE-ASSOCIATED MEMORY IMPAIRMENT - DIAGNOSTIC-CRITERIA AND TREATMENT STRATEGIES
CROOK, T
LARRABEE, GJ
PSYCHOPHARMACOLOGY BULLETIN, 1988, 24 (04) : 509 - 514
[50] Facilitation of glutamate receptors reverses an age-associated memory impairment in rats
Granger, R
Deadwyler, S
Davis, M
Moskovitz, B
Kessler, M
Rogers, G
Lynch, G
SYNAPSE, 1996, 22 (04) : 332 - 337

← 1 2 3 4 5 →