Nocardia harenae, an uncommon causative organism of mycetoma: report on two patients

被引:9
|
作者
Kresch-Tronik, Nicole S. [5 ]
Carrillo-Casas, Erika M. [2 ]
Arenas, Roberto [3 ]
Atoche, Carlos [4 ]
Ochoa-Carrera, Luis A. [1 ]
Xicohtencatl-Cortes, Juan [6 ]
Manjarrez-Hernandez, Angel H. [7 ]
Hernandez-Castro, Rigoberto [1 ]
机构
[1] Hosp Gen Dr Manuel Gea Gonzalez, Dept Ecol Agentes Patogenos, Tlalpan 14080, Mexico
[2] Hosp Gen Dr Manuel Gea Gonzalez, Dept Biol Mol & Histocompatibilidad, Tlalpan 14080, Mexico
[3] Hosp Gen Dr Manuel Gea Gonzalez, Dept Micol, Tlalpan 14080, Mexico
[4] Ctr Dermatol Dr Fernando Latapi, Dept Micol, Merida, Yucatan, Mexico
[5] Hosp Gen Dr Manuel Gea Gonzalez, Serv Dermatol, Tlalpan 14080, Mexico
[6] Hosp Infantil Mexico Dr Federico Gomez, Dept Infectol, Mexico City, DF, Mexico
[7] Univ Nacl Autonoma Mexico, Fac Med, Dept Salud Publ, Mexico City 04510, DF, Mexico
关键词
RNA GENE-SEQUENCES; FEATURES;
D O I
10.1099/jmm.0.042044-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Mycetonna is the most frequently diagnosed deep mycosis in Mexico and is caused, in 86% of cases, by Nocardia brasiliensis. Worldwide, Nocardia harenae has not been previously reported as a causative agent of human mycetoma. Herein we report, to our knowledge, the first two human cases of mycetoma due to N. harenae in a clinical setting. The strains were identified by phenotypic and molecular techniques. Both cases were characterized by long-lasting mycetoma that had previously been failed to be cured and had shown resistance to therapy. However, in our hospital, a multidrug therapy proved to be effective in these cases.
引用
收藏
页码:1153 / 1155
页数:3
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