One-pot multicomponent synthesis of polyhydroquinolines under catalyst and solvent-free conditions

被引:19
|
作者
Das, Sudarshan [1 ]
Santra, Sougata [1 ]
Roy, Anupam [1 ]
Urinda, Sharmistha [1 ]
Majee, Adinath [1 ]
Hajra, Alakananda [1 ]
机构
[1] Visva Bharati Univ, Dept Chem, Santini Ketan 731235, W Bengal, India
关键词
Hantzsch condensation; polyhydroquinolines; microwave; catalyst and solvent-free; four-component; CONDENSATION;
D O I
10.1080/17518253.2011.584073
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An efficient one-pot condensation has been developed for the synthesis of polyhydroquinolines via a four component coupling reaction of aldehyde, dimedone, ethyl acetoacetate, and ammonium acetate under catalyst and solvent-free conditions. Non-hazardous experiment procedure, operational simplicity, mild reaction conditions, and the compatibility with various functional groups represent the advantages of the present method. [GRAPHICS] .
引用
收藏
页码:97 / 100
页数:4
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