TCF-1 and LEF-1 help launch the TFH program

被引:3
|
作者
Kubo, Masato [1 ,2 ]
机构
[1] Tokyo Univ Sci, Res Inst Biomed Sci, Chiba, Japan
[2] RIKEN, Ctr Integrat Med Sci IMS, Yokohama, Kanagawa, Japan
关键词
CELL DIFFERENTIATION; PATHWAY; FATE;
D O I
10.1038/ni.3254
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Follicular helper T cells (T-FH cells) differentiate from naive T cells, but the picture of this differentiation process remains incomplete. Two studies now identify the related transcriptional regulators TCF-1 and LEF-1 as important early participants in this process.
引用
收藏
页码:900 / 901
页数:2
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