Discovery and development of Santacruzamate A, a potent and selective histone deacetylase inhibitor

被引：0
|
作者：
Balunas, M. J. [1 ,2 ,3 ,4 ]
Pavlik, C. M. [1 ]
Wong, C. Y. B. [4 ]
Lopez, D. D. [4 ]
Engene, N. [2 ]
McPhail, K. [5 ]
Gerwick, W. H. [2 ,3 ]
机构：
[1] Univ Connecticut, Dept Pharmaceut Sci, Div Med Chem, Storrs, CT USA
[2] Univ Calif San Diego, Ctr Marine Biotechnol & Biomed, Scripps Inst Oceanog, La Jolla, CA 92093 USA
[3] Smithsonian Trop Res Inst, Panama City, Panama
[4] INDICASAT, Panama City, Panama
[5] Oregon State Univ, Coll Pharm, Corvallis, OR 97331 USA
来源：
PLANTA MEDICA | 2012年 / 78卷 / 11期
关键词：
D O I：
暂无
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
引用
收藏
页码：1050 / 1050
页数：1
相关论文
共 50 条
  • [31] Discovery of a novel histone deacetylase 8 inhibitor by virtual screening
    Lei Zhang
    Minyong Li
    Jinhong Feng
    Hao Fang
    Wenfang Xu
    Medicinal Chemistry Research, 2012, 21 : 152 - 156
  • [32] Discovery of a novel histone deacetylase 8 inhibitor by virtual screening
    Zhang, Lei
    Li, Minyong
    Feng, Jinhong
    Fang, Hao
    Xu, Wenfang
    MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (02) : 152 - 156
  • [33] Discovery of a series of hydroximic acid derivatives as potent histone deacetylase inhibitors
    Zhang, Lei
    Wang, Xuejian
    Li, Xiaoguang
    Zhang, Lihui
    Xu, Wenfang
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2014, 29 (04) : 582 - 589
  • [34] Tropolones As Lead-Like Natural Products: The Development of Potent and Selective Histone Deacetylase Inhibitors
    Ononye, Sophia N.
    VanHeyst, Michael D.
    Oblak, E. Zachary
    Zhou, Wangda
    Ammar, Mohamed
    Anderson, Amy C.
    Wright, Dennis L.
    ACS MEDICINAL CHEMISTRY LETTERS, 2013, 4 (08): : 757 - 761
  • [35] MEDI 334-Discovery, optimization and biological evaluation of novel, potent and selective histone deacetylase (HDAC) inhibitors
    Namdev, Nivedita D.
    Tandon, Manish
    Akireddy, Rao
    Orgueira, Hernan
    Vensel, David
    Kung, Ming
    Wu, Hui
    Hutchins, Patrick
    Moussa, Magdi
    Link, Jeffrey
    Liu, Yanbin
    Nicewonger, Robb
    Bruseo, Charles
    Gorenstein, Julie
    Nakuci, Enkeleda
    McSweeney, Denise
    Bresciano, Karen
    Wang, Yunxia
    France, Dennis
    Ashwell, Mark A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234
  • [36] Histone deacetylase inhibitors: discovery and development as anticancer agents
    Marks, PA
    Dokmanovic, M
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2005, 14 (12) : 1497 - 1511
  • [37] Synthesis and analysis of spiruchostatin A, a potent bicyclic tetrapeptide histone deacetylase inhibitor
    Packham, G
    Yurek-George, A
    Habens, F
    Brimmell, M
    Ganesan, A
    BRITISH JOURNAL OF CANCER, 2004, 91 : S63 - S63
  • [38] Potent and Selective Non-hydroxamate Histone Deacetylase 8 Inhibitors
    Kleinschek, Alexander
    Meyners, Christian
    Digiorgio, Eros
    Brancolini, Claudio
    Meyer-Almes, Franz-Josef
    CHEMMEDCHEM, 2016, 11 (23) : 2598 - 2606
  • [39] Discovery of a potent and selective Aurora kinase inhibitor
    Oslob, Johan D.
    Romanowski, Michael J.
    Allen, Darin A.
    Baskaran, Subramanian
    Bui, Minna
    Elling, Robert A.
    Flanagan, William M.
    Fung, Amy D.
    Hanan, Emily J.
    Harris, Shannon
    Heumann, Stacey A.
    Hoch, Ute
    Jacobs, Jeffrey W.
    Lam, Joni
    Lawrence, Chris E.
    McDowell, Robert S.
    Nannini, Michelle A.
    Shen, Wang
    Silverman, Jeffrey A.
    Sopko, Michelle M.
    Tangonan, Bradley T.
    Teague, Juli
    Yoburn, Josh C.
    Yu, Chul H.
    Zhong, Min
    Zimmerman, Kristin M.
    O'Brien, Tom
    Lew, Willard
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (17) : 4880 - 4884
  • [40] How do we improve histone deacetylase inhibitor drug discovery?
    Hamze, Abdallah
    EXPERT OPINION ON DRUG DISCOVERY, 2020, 15 (05) : 527 - 529
12345