Pd-Cu-Mediated Synthesis of 2-Substituted Imidazo[1,2-A]pyridines in Water

被引:8
|
作者
Bakherad, Mohammad [1 ]
Keivanloo, Ali [1 ]
Hashemi, Mahdieh [1 ]
机构
[1] Shahrood Univ Technol, Fac Chem, Shahrood 3619995161, Iran
关键词
Aryl iodide; imidazopyridine; Pd-catalyzed; sodium lauryl sulfate; Sonogashira coupling; SONOGASHIRA COUPLING REACTION; CATALYZED HETEROCYCLIZATION; ARYL CHLORIDES; AQUEOUS-MEDIA; DERIVATIVES; ALKYNES;
D O I
10.1080/00397910802448499
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The reaction of 2-amino-1-(2-propynyl)pyridinium bromide with various iodobenzenes, catalyzed by Pd-Cu, in the presence of sodium lauryl sulfate as the surfactant and cesium carbonate as the base, in water, leads to the formation of 2-substituted imidazo[1,2-]pyridines.
引用
收藏
页码:1002 / 1011
页数:10
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