Micro-/Nanomotors toward Biomedical Applications: The Recent Progress in Biocompatibility

被引:132
|
作者
Ou, Juanfeng [1 ,2 ]
Liu, Kun [2 ]
Jiang, Jiamiao [2 ]
Wilson, Daniela A. [3 ]
Liu, Lu [2 ]
Wang, Fei [2 ]
Wang, Shuanghu [2 ]
Tu, Yingfeng [2 ]
Peng, Fei [1 ]
机构
[1] Sun Yat Sen Univ, Sch Mat Sci & Engn, Guangzhou 510275, Peoples R China
[2] Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R China
[3] Radboud Univ Nijmegen, Inst Mol & Mat, NL-6525 AJ Nijmegen, Netherlands
基金
中国国家自然科学基金;
关键词
biocompatibility; biodegradability; biomedical applications; micro-; nanomotors; self-propulsion; STOMATOCYTE NANOMOTORS; INTRACELLULAR DELIVERY; PROPELLED MICROMOTORS; CELL; PROPULSION; DRIVEN; MOTION; TRANSPORTATION; MICROENGINES; FABRICATION;
D O I
10.1002/smll.201906184
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Inspired by the highly versatile natural motors, artificial micro-/nanomotors that can convert surrounding energies into mechanical motion and accomplish multiple tasks are devised. In the past few years, micro-/nanomotors have demonstrated significant potential in biomedicine. However, the practical biomedical applications of these small-scale devices are still at an infant stage. For successful bench-to-bed translation, biocompatibility of micro-/nanomotor systems is the central issue to be considered. Herein, the recent progress in micro-/nanomotors in biocompatibility is reviewed, with a special focus on their biomedical applications. Through close collaboration between researches in the nanoengineering, material chemistry, and biomedical fields, it is expected that a promising real-world application platform based on micro-/nanomotors will emerge in the near future.
引用
收藏
页数:16
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